Plasma Modification of Polymer Surfaces and Their Utility in Building Biomedical Microdevices
Plasma Modification of Polymer Surfaces and Their Utility in Building Biomedical Microdevices
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DOI：
10.1163/016942410x511105
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发表时间：
2010-01-01
影响因子：
2.3
通讯作者：
Gangopadhyay, Shubhra
中科院分区：
文献类型：
--
作者：
Bhattacharya, Shantanu;Singh, Rajeev Kr.;Gangopadhyay, Shubhra
聚合物被广泛用于生物检测和传感的微系统中，并为生物医学微器件（BMMD）的制造提供更容易的替代品。最广泛使用的适于微加工的聚合物体系是硅橡胶，特别是聚（二甲基硅氧烷）（PDMS）。硅橡胶提供的主要优点是它能够通过微成型以高纵横比进行复制。除了PDMS，其他聚合物系统，如抗蚀剂或环氧树脂，发现在微制造提供了许多方面，如良好的层间结合，选择性图案化，修改的物理性能，如可变的电气或光学性能等，大多数聚合物系统是服从其表面能的快速变化，因为它们暴露于气体等离子体或紫外线辐射。这种变化有时是可逆的，并且暴露的表面可以随着时间的推移恢复其原始配置，称为疏水恢复。一般来说，经过此类外部刺激后，聚合物表面在结构上变得高度动态，这使得它们非常适合BMMD制造中的重要应用。我们的小组在通过外部刺激进行聚合物表面改性及其表征领域进行了广泛的工作，在本文中我们试图回顾该小组的一些工作。(C)Koninklijke Brill NV，莱顿，2010年
Polymers are widely used in micro-systems for biological detection and sensing and to provide easier alternatives for fabrication of Biomedical Micro-devices (BMMDs). The most widely used polymeric system amenable to micro-fabrication is silicone rubber, particularly poly(dimethylsiloxane) (PDMS). The principal advantage that silicone rubber offers is its ability to get replicated with high aspect ratios by micro-molding. In addition to PDMS, other polymer systems, like resists or epoxies, find extensive use in micro-fabrication providing many aspects such as good interlayer bonding, selective patterning, modified physical properties like variable electrical or optical properties, etc. Most polymer systems are amenable to rapid changes in their surface energies as they are exposed to gas plasmas or UV radiation. Such changes can sometimes be reversible and the exposed surfaces can regain their original configuration with time called hydrophobic recovery. In general, polymer surfaces after such external stimuli become constitutionally highly dynamic and this makes them well suited to prominent applications in fabrication of BMMDs. Our group has extensively worked in the area of polymer surface modification by external stimuli and its characterization and in this paper we have attempted to review some of the group's work. (C) Koninklijke Brill NV, Leiden, 2010