High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s
High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s
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DOI：
10.1364/boe.5.002963
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发表时间：
2014-09-01
影响因子：
3.4
通讯作者：
Huber, Robert
中科院分区：
文献类型：
--
作者：
Wieser, Wolfgang;Draxinger, Wolfgang;Huber, Robert
我们提出了一个1300 nm的OCT系统，体积实时实时OCT采集和可视化，每秒10亿体积元素。所有的技术挑战和问题与这样的高扫描速度进行了详细讨论，以及解决方案。在一种配置中，系统每秒采集、处理和可视化26个体积，其中每个体积由320 X 320个深度扫描组成，并且每个深度扫描具有400个可用像素。这是迄今为止在体素速率方面最快的实时OCT。51 Hz的音量速率是用一半的帧数实现的。在这两种配置中，速度可以无限期地保持。OCT系统使用以3.2 MHz扫描速率操作的1310 nm傅立叶域锁模（FDML）激光器。数据采集是用两个专用的数字化卡进行的，每个数字化卡以2.5 GS/s的速度运行，托管在一台台式计算机上。现场实时数据处理和可视化是通过NVidia GTX 690双图形处理单元（GPU）卡上的定制开发软件实现的。为了评估这种系统未来的潜在应用，我们提出了体积视频捕获在26和51赫兹的浮游甲壳类动物和皮肤。2014美国光学学会Optical Society of America
We present a 1300 nm OCT system for volumetric real-time live OCT acquisition and visualization at 1 billion volume elements per second. All technological challenges and problems associated with such high scanning speed are discussed in detail as well as the solutions. In one configuration, the system acquires, processes and visualizes 26 volumes per second where each volume consists of 320 x 320 depth scans and each depth scan has 400 usable pixels. This is the fastest real-time OCT to date in terms of voxel rate. A 51 Hz volume rate is realized with half the frame number. In both configurations the speed can be sustained indefinitely. The OCT system uses a 1310 nm Fourier domain mode locked (FDML) laser operated at 3.2 MHz sweep rate. Data acquisition is performed with two dedicated digitizer cards, each running at 2.5 GS/s, hosted in a single desktop computer. Live real-time data processing and visualization are realized with custom developed software on an NVidia GTX 690 dual graphics processing unit (GPU) card. To evaluate potential future applications of such a system, we present volumetric videos captured at 26 and 51 Hz of planktonic crustaceans and skin. (C)2014 Optical Society of America