BLUF: a novel FAD-binding domain involved in sensory transduction in microorganisms
BLUF: a novel FAD-binding domain involved in sensory transduction in microorganisms
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DOI：
10.1016/s0968-0004(02)02181-3
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发表时间：
2002-10-01
影响因子：
13.8
通讯作者：
Klug, G
中科院分区：
文献类型：
--
作者：
Gomelsky, M;Klug, G
一种新的FAD结合结构域，BLUE，以来自球形红细菌的AppA蛋白的N-末端为例，存在于各种蛋白质中，主要来自细菌。BLUF结构域参与使用FAD感测蓝光（和可能的氧化还原），并且类似于黄素结合PAS结构域和隐花色素。预测的二级结构揭示了BLUF结构域是一种新的FAD结合折叠。
A novel FAD-binding domain, BLUE exemplified by the N-terminus of the AppA protein from Rhodobacter sphaeroides, is present in various proteins, primarily from Bacteria. The BLUF domain is involved in sensing blue-light (and possibly redox) using FAD and is similar to the flavin-binding PAS domains and cryptochromes. The predicted secondary structure reveals that the BLUF domain is a novel FAD-binding fold.