Diabetes does not affect motor recovery after intracerebral hemorrhage.
Diabetes does not affect motor recovery after intracerebral hemorrhage.
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DOI：
10.1515/tnsci-2020-0125
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发表时间：
2020
影响因子：
2.1
通讯作者：
Chang MC
中科院分区：
文献类型：
--
作者：
Jang SH;Kwak SG;Chang MC
本回顾性研究通过控制脑卒中期间病变类型和部位、皮质脊髓束状态、患者年龄、病变体积和治疗方法等关键因素，分析糖尿病对脑卒中后运动预后的影响，评估糖尿病是否影响脑卒中后运动预后。我们招募了221例基底神经节脑出血（ICH）患者。我们用扩散张量束图研究CST状态。我们还评估了出血量。我们通过图表回顾获得了糖尿病的存在和年龄的信息。6个月时的运动结果采用上肢和下肢运动指数（MI）、改良Brunnstrom分类（MBC）和功能行走分类（FAC）进行测量。我们采用多元线性回归检验，在调整CST状态、年龄、病变体积和治疗方法等其他因素后，探讨糖尿病是否会影响卒中后的运动预后。在发病后6个月，糖尿病的存在与运动结果测量无关，包括上下MIs、MBC和FAC。然而，CST状态、年龄、病变体积和治疗方法与几乎所有运动预后均显著相关。我们发现糖尿病对脑出血后的运动预后没有显著影响。
This retrospective study evaluated whether diabetes affects motor outcome after stroke by analyzing the effects of diabetes on motor prognosis by controlling for critical factors, including lesion type and location, corticospinal tract (CST) state, patient age, lesion volume, and treatment method during the stroke. We recruited 221 patients with intracerebral hemorrhage (ICH) of the basal ganglia. We used diffusion tensor tractography to investigate the CST state. We also evaluated the hemorrhage volume. We obtained information on the presence of diabetes and age by chart review. Motor outcomes at 6 months were measured using the upper and lower limb motricity index (MI), modified Brunnstrom classification (MBC), and functional ambulation category (FAC). We used multiple linear regression tests to investigate whether diabetes affected motor outcomes after stroke after adjusting for other factors, including CST state, age, lesion volume, and treatment method. The presence of diabetes was not correlated with motor outcome measurements, including upper and lower MIs, MBC, and FAC, at 6 months after the onset. However, the CST state, age, lesion volume, and treatment method were significantly correlated with nearly all motor outcomes. We found that diabetes did not significantly affect motor outcomes after ICH.
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影响因子：
16.2
作者：
American Diabetes Association
通讯作者：
American Diabetes Association
影响因子：
2.6
作者：
Yoo JS;Choi BY;Chang CH;Jung YJ;Kim SH;Jang SH
通讯作者：
Jang SH
影响因子：
8.3
作者：
Cheng, Bastian;Forkert, Nils Daniel;Thomalla, Goetz
通讯作者：
Thomalla, Goetz
DOI：
10.1097/00002060-200211000-00008
发表时间：
2002-11-01
影响因子：
3
作者：
Cunha, IT;Lim, PAC;Protas, EJ
通讯作者：
Protas, EJ
影响因子：
8.3
作者：
Bagg, S;Pombo, AP;Hopman, W
通讯作者：
Hopman, W