Intra-aneurysmal blood flow based on patient-specific CT angiogram

Intra-aneurysmal blood flow based on patient-specific CT angiogram
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DOI:
10.1007/s00348-009-0816-1
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发表时间:
2010-08-01
影响因子:
2.4
通讯作者:
Tanishita, Kazuo
Tanishita, Kazuo
中科院分区:
工程技术3区
文献类型:
--
作者:
Morino, Taku;Tanoue, Tetsuya;Tanishita, Kazuo

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为了讨论动脉瘤破裂的血流动力学假设的有效性,我们使用了一个患者特定的,现实的动脉瘤模型,以揭示两种情况下的流动结构和壁面剪切应力分布:一个未破裂的动脉瘤,另一个破裂的动脉瘤。我们使用粒子成像测速仪和激光多普勒测速仪来测量动脉瘤内血流的速度分布。两个病例都有沿着动脉瘤壁的循环流,尽管第二个病例仅在最小相位有再循环区。壁面剪切应力分布的差异可识别动脉瘤破裂。
To discuss the validity of the hemodynamic hypothesis of aneurysm rupture, we used a patient-specific, realistic aneurysm model to reveal the flow structure and wall shear stress distribution in two cases: one with an unruptured aneurysm and the other with a ruptured aneurysm. We used particle imaging velocimetry and laser Doppler velocimetry to measure velocity profiles of intra-aneurysmal flow. Both cases had a circulating flow along the aneurysm wall, although the second case had a recirculating zone only in the minimum phase. Differences in the wall shear stress profile may identify aneurysm rupture.