Transitions in neural oscillations reflect prediction errors generated in audiovisual speech
Transitions in neural oscillations reflect prediction errors generated in audiovisual speech
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DOI：
10.1038/nn.2810
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发表时间：
2011-06-01
影响因子：
25
通讯作者：
Giraud, Anne-Lise
中科院分区：
文献类型：
--
作者：
Arnal, Luc H.;Wyart, Valentin;Giraud, Anne-Lise
根据预测编码理论，自上而下的预测通过后向连接传递，并且预测误差在大脑皮层层级中向前传播。在人类中使用脑磁图，我们表明，违反多感官预测会导致皮层活动的频率和空间分布发生根本性和质的变化。当视觉语音输入正确预测听觉语音信号时，在高阶语音区形成了一个慢增量区(3-4赫兹)。相反，当听觉信号使从视觉推断的预测失效时，低贝塔(14-15赫兹)/高伽马(60-80赫兹)耦合区域在多感觉区(STS区)局部出现。振荡反应的这种频率变化随着视听一致性程度的增加而增加，并伴随着较低感觉区域伽马活动的增加。这些发现与以下观点一致，即自下而上的预测误差主要在高(伽马)频率范围内传递，而自上而下的预测则通过较慢的(贝塔)频率进行传递。
According to the predictive coding theory, top-down predictions are conveyed by backward connections and prediction errors are propagated forward across the cortical hierarchy. Using MEG in humans, we show that violating multisensory predictions causes a fundamental and qualitative change in both the frequency and spatial distribution of cortical activity. When visual speech input correctly predicted auditory speech signals, a slow delta regime (3-4 Hz) developed in higher-order speech areas. In contrast, when auditory signals invalidated predictions inferred from vision, a low-beta (14-15 Hz) / high-gamma (60-80 Hz) coupling regime appeared locally in a multisensory area (area STS). This frequency shift in oscillatory responses scaled with the degree of audio-visual congruence and was accompanied by increased gamma activity in lower sensory regions. These findings are consistent with the notion that bottom-up prediction errors are communicated in predominantly high (gamma) frequency ranges, whereas top-down predictions are mediated by slower (beta) frequencies.