Australian Aboriginal people and Torres Strait Islanders have an atherogenic lipid profile that is characterised by low HDL-cholesterol level and small LDL particles
Australian Aboriginal people and Torres Strait Islanders have an atherogenic lipid profile that is characterised by low HDL-cholesterol level and small LDL particles
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DOI：
10.1016/j.atherosclerosis.2008.03.022
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发表时间：
2008-12-01
期刊：
影响因子：
5.3
通讯作者：
O'Dea, K.
中科院分区：
文献类型：
--
作者：
O'Neal, D. N.;Piers, L. S.;O'Dea, K.
目的：表征澳大利亚土著人和托雷斯海峡岛民的脂质谱。方法：1995-1997年以社区为基础的横断面调查，包括：澳大利亚土著居民女性407人，男性322人；15岁以上托雷斯海峡岛民女性207人，男性186人。临床流行病学研究招募了78名非土著女性（44名糖尿病患者）和148名男性（73名糖尿病患者）作为比较对象。脂质采用标准法测定，LDL直径采用梯度凝胶电泳测定。结果：原住民和托雷斯海峡岛民的糖尿病患病率分别为14.8%和22.6%。分别。LDL大小（平均95% CI（置信区间））较小(P
Aim: To characterise lipid profiles for Australian Aboriginal people and Torres Strait Islanders.Methods: Community-based, cross-sectional surveys in 1995-1997 including: 407 female and 322 male Australian Aboriginal people and 207 female and 186 male Torres Strait Islanders over 15 years old. A comparator of 78 female (44 with diabetes) and 148 male (73 with diabetes) non-indigenous participants recruited to clinical epidemiological Studies was used. Lipids were determined by standard assays and LDL diameter by gradient gel electrophoresis.Results: Diabetes prevalence was 14.8% and 22.6% among, Aboriginal people and Torres Strait Islanders. respectively. LDL size (mean [95% CI (confidence interval) was smaller (P