Paths less traveled: evo-devo approaches to investigating animal morphological evolution.

Paths less traveled: evo-devo approaches to investigating animal morphological evolution.
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DOI:
10.1146/annurev-cellbio-101011-155732
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发表时间:
2012
影响因子:
11.3
通讯作者:
Abzhanov A
Abzhanov A
中科院分区:
生物学1区
文献类型:
--
作者:
Mallarino R;Abzhanov A

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现代生物学的主要目标之一是了解形态进化的原因和机制。多细胞动物的身体和个体亚有机结构的形状和大小具有惊人的多样性,其中大部分对它们的生存很重要。研究形态多样性进化的最有效方法是什么?进化发育生物学 (evo-devo) 的新旧领域对于理解动物形态的起源特别有用,因为它旨在巩固系统发生学、基因组学、形态测量学、细胞生物学和发育生物学等不同领域的进展。我们分析了最近一些最成功的 evo-devo 研究的结构,我们认为这些研究具有三个不同但高度相互依赖的组成部分:(a)形态计量学,(b)候选机制的识别,以及(c)功能实验。我们的案例研究说明了三翼进化-发育研究计划中采用的多种进化-发育方法如何解释不同系统发育尺度的形态进化的发育机制。
One of the chief aims of modern biology is to understand the causes and mechanisms of morphological evolution. Multicellular animals display a stunning diversity of shapes and sizes of their bodies and individual suborganismal structures, much of it important to their survival. What is the most efficient way to study the evolution of morphological diversity? The old-new field of evolutionary developmental biology (evo-devo) can be particularly useful for understanding the origins of animal forms, as it aims to consolidate advances from disparate fields such as phylogenetics, genomics, morphometrics, cell biology, and developmental biology. We analyze the structure of some of the most successful recent evo-devo studies, which we see as having three distinct but highly interdependent components: (a) morphometrics, (b) identification of candidate mechanisms, and (c) functional experiments. Our case studies illustrate how multifarious evo-devo approaches taken within the three-winged evo-devo research program explain developmental mechanisms for morphological evolution across different phylogenetic scales.
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