The dependence of transversely isotropic elasticity of human femoral cortical bone on porosity
The dependence of transversely isotropic elasticity of human femoral cortical bone on porosity
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DOI：
10.1016/j.jbiomech.2003.12.011
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发表时间：
2004-08-01
影响因子：
2.4
通讯作者：
Guo, XE
中科院分区：
文献类型：
--
作者：
Dong, XN;Guo, XE
本研究的目的是考察作为横观各向同性材料的皮质骨的弹性性能与其孔隙率的关系。在液压伺服材料试验机上进行了18组纵向和横向试件的拉伸和扭转试验，测定了皮质骨的纵向杨氏模数、横向杨氏模数、纵向剪切模数、横向剪切模数和纵向泊松比。这些圆柱形腰部皮质骨标本取自三对人股骨中段骨干。通过组织学的方法评估这些标本的孔隙率。我们的研究表明，人股骨皮质骨的纵向杨氏模数和剪切模数与皮质骨的孔隙率呈显著负相关(p<；0.01)。相反，横向的弹性性能与皮质骨的孔隙率没有统计学上的显著相关性。因此，皮质骨的横向弹性特性对孔隙率的变化比纵向的变化不那么敏感。此外，皮质骨弹性的各向异性比率与其孔隙率呈显著负相关(p<；0.01)，表明随着孔隙率的增加，皮质骨的各向同性倾向于变得更加各向同性。这些结果可能有助于一些研究人员开发更精确的皮质骨微观力学模型。(C)2003爱思唯尔有限公司。保留所有权利。
The objective of this study was to examine the dependence of the elastic properties of cortical bone as a transversely isotropic material on its porosity. The longitudinal Young's modulus, transverse Young's modulus, longitudinal shear modulus, transverse shear modulus, and longitudinal Poisson's ratio of cortical bone were determined from eighteen groups of longitudinal and transverse specimens using tensile and torsional tests on a servo-hydraulic material testing system. These cylindrical waisted specimens of cortical bone were harvested from the middle diaphysis of three pairs of human femora. The porosity of these specimens was assessed by means of histology. Our study demonstrated that the longitudinal Young's and shear Moduli of human femoral cortical bone were significantly (p < 0.01) negatively correlated with the porosity of cortical bone. Conversely, the elastic properties in the transverse direction did not have statistically significant correlations with the porosity of cortical bone. As a result, the transverse elastic properties of cortical bone were less sensitive to changes in porosity than those in the longitudinal direction. Additionally, the anisotropic ratios of cortical bone elasticity were found to be significantly (p < 0.01) negatively correlated with its porosity, indicating that cortical bone tended to become more isotropic when its porosity increased. These results may help a number of researchers develop more accurate micromechanics models of cortical bone. (C) 2003 Elsevier Ltd. All rights reserved.