Intravenous augmentative citalopram versus clomipramine in partial/nonresponder depressed patients - A short-term, low dose, randomized, placebo-controlled study
Intravenous augmentative citalopram versus clomipramine in partial/nonresponder depressed patients - A short-term, low dose, randomized, placebo-controlled study
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DOI：
10.1097/jcp.0b013e31817d5931
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发表时间：
2008-08-01
影响因子：
2.9
通讯作者：
Mundo, Emanuela
中科院分区：
文献类型：
--
作者：
Altamura, Alfredo Carlo;Dell'Osso, Bernardo;Mundo, Emanuela
本研究的目的是在一组对选择性5-羟色胺再摄取抑制剂(SSRIs)有部分反应或无反应的MDE患者中，比较短期小剂量静脉注射西酞普兰(10 mg/d)与氯丙咪嗪(25 mg/d)与安慰剂的疗效。54名精神疾病诊断和统计手册第四版，文本修订版，MDE，每OS对SSRI部分或无反应的患者(21项汉密尔顿抑郁评定量表[HAM-D-21]减分，
The aim of the present study was to evaluate the efficacy of short-term low-dose intravenous augmentative citalopram (10mg/d) versus clomipramine (25mg/d) versus placebo in a sample of patients with MDE and partial or no response to selective serotonin reuptake inhibitors (SSRIs). Fifty-four patients with a Diagnostic and Statistical Manual of Mental Disorders' Fourth Edition, Text Revision, MDE and partial or no response to SSRIs per os (21-item Hamilton Depression Rating Scale [HAM-D-21] score reduction,