Current prescribing trends of antibiotics by dentists in Australia from 2013 to 2016. Part 1.
Current prescribing trends of antibiotics by dentists in Australia from 2013 to 2016. Part 1.
复制标题
DOI：
10.1111/adj.12622
复制
发表时间：
2018-09-01
影响因子：
2.1
通讯作者：
McCullough, M. J.
中科院分区：
文献类型：
--
作者：
Teoh, L.;Stewart, K.;McCullough, M. J.
文献表明，牙医倾向于过度使用抗生素，而且并不总是按照建议的指导方针开处方。不必要的处方是导致抗生素耐药性发展的一个主要因素。本研究的目的是评估2013年至2016年澳大利亚牙医的抗菌药物处方模式。方法获取2013 - 2016年药品福利计划（PBS）下口腔抗菌药物处方数据，分析处方趋势。处方率根据剂量和人群标准化。结果2013 - 2016年，大部分抗菌药物的配用用量略有下降，但阿莫西林/克拉维酸的配用用量显著增加，增幅为11.2%。阿莫西林是最常用的抗生素，占2013 - 2016年所有抗菌药物的约65%，而苯氧苄青霉素仅占2016年处方的1.4%。分发的抗生素处方不符合现行指南，数量虽少，但意义重大。结论数据表明，澳大利亚的牙医在处方一些抗生素时存在不当，并且更倾向于使用中广谱药物。目前的PBS牙科时间表与处方指南不一致，可能导致不适当的处方。
BackgroundLiterature has shown dentists tend to overprescribe antibiotics and do not always prescribe in accordance with recommended guidelines. Unnecessary prescribing is one major factor that contributes to the development of antibiotic resistance. The aim of the present study was to assess the antibacterial prescribing patterns of dentists in Australia from 2013 to 2016.MethodsData on dental antibacterial prescriptions dispensed under the Pharmaceutical Benefits Scheme(PBS) from 2013 to 2016 was accessed and prescribing trends analysed. The prescribing rates were standardized to the dose and population.ResultsThere was a slight decrease in the dispensed use of most antibacterials from 2013 to 2016, but there was a significant increase in the dispensed use of amoxicillin/clavulanic acid of 11.2%. Amoxicillin was the most commonly dispensed antibiotic, accounting for approximately 65% of all antibacterials from 2013 to 2016, while phenoxymethylpenicillin accounted for only 1.4% of prescriptions in 2016. There were low but significant quantities of dispensed antibiotic prescriptions that do not fit with current guidelines.ConclusionsThe data suggest that dentists in Australia are prescribing some antibiotics inappropriately and there is a preference for moderate- to broad-spectrum agents. The current PBS dental schedule is inconsistent with prescribing guidelines and may contribute to inappropriate prescribing.