Photo-driven expulsion of molecules from mesostructured silica nanoparticles
Photo-driven expulsion of molecules from mesostructured silica nanoparticles
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DOI：
10.1021/jp0707211
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发表时间：
2007-05-10
影响因子：
3.7
通讯作者：
Zink, Jeffrey I.
中科院分区：
文献类型：
--
作者：
Angelos, Sarah;Choi, Eunshil;Zink, Jeffrey I.
偶氮苯衍生物在介孔二氧化硅纳米颗粒内和表面同时起着推动者和看门人的作用。在457 nm（顺式和反式构象都吸收的波长）处连续激发，产生持续的异构化反应，并导致无系链末端的持续动态摆动。在直径为2 nm的孔中加载发光探针分子，光刺激偶氮苯运动，并通过发光光谱学监测由运动引起的探针从颗粒中的光诱导排出。这些材料的光响应特性使它们能够被外部控制，从而可以随意启动和停止染料分子从介孔中的排出。这些结果开启了捕获有用分子（如药物）并按需释放它们的可能性。
Azobenzene derivatives act as both impellers and gatekeepers when they are tethered in and on mesoporous silica nanoparticles. Continuous excitation at 457 nm, a wavelength where both the cis and trans conformers absorb, produces constant isomerization reactions and results in continual dynamic wagging of the untethered terminus. The 2 nm diameter pores are loaded with luminescent probe molecules, azobenzene motion is stimulated by light, and the photoinduced expulsion of the probe from the particles that is caused by the motion is monitored by luminescence spectroscopy. The light-responsive nature of these materials enables them to be externally controlled such that the expulsion of dye molecules from the mesopores can be started and stopped at will. These results open the possibilities of trapping useful molecules such as drugs and releasing them on demand.