Polyoxometalate-Driven Self-Assembly of Short Peptides into Multivalent Nanofibers with Enhanced Antibacterial Activity
Polyoxometalate-Driven Self-Assembly of Short Peptides into Multivalent Nanofibers with Enhanced Antibacterial Activity
复制标题
多金属氧酸盐驱动的短肽自组装成具有增强抗菌活性的多价纳米纤维
DOI：
10.1002/anie.201511276
复制
发表时间：
2016-02-12
影响因子：
16.6
通讯作者：
Lee, Myongsoo
中科院分区：
文献类型：
--
作者：
Li, Jingfang;Chen, Zhijun;Lee, Myongsoo
Multivalent peptide nanofibers have attracted intense attention as promising platforms, but the fabrication of those nanofibers is mainly dependent on the spontaneous assembly of beta-sheet peptides. Herein we report an alternative approach to the creation of nanofibers: the polyoxometalatedriven self-assembly of short peptides. The resultant nanofibers with concentrated positive charges are excellent multivalent ligands for binding with bacterial cells and thus lead to a salient improvement in bioactivity.
