Transport-based image reconstruction in turbid media with small source-detector separations
Transport-based image reconstruction in turbid media with small source-detector separations
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DOI：
10.1364/ol.25.001777
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发表时间：
2000-12-15
期刊：
影响因子：
3.6
通讯作者：
Boas, D
中科院分区：
文献类型：
--
作者：
Dunn, A;Boas, D
我们展示了一种新的方法，通过结合共聚焦反射显微镜和漫反射光学层析成像，通过几毫米的混浊样品，分辨率约为100微米。通过横向移动共焦显微镜的针孔孔径，我们可以实现小源-探测器的分离，并检测到最小的散射光。然后使用基于辐射传输方程的一阶Born近似的重建算法来重建位于表面下2 mm处的100微米吸收对象的图像。(C)2000年美国光学学会。
We demonstrate a new method for imaging through several millimeters of a turbid sample with a resolution of approximately 100 mum by combining aspects of confocal reflectance microscopy and diffuse optical tomography. By laterally displacing the pinhole aperture of a confocal microscope we can achieve small source-detector separations and detect minimally scattered light. A reconstruction algorithm based on the first Born approximation to the radiative transport equation is then used to reconstruct an image of a 100-mum absorbing object located 2 mm beneath the surface. (C) 2000 Optical Society of America.