A neutronic study of an accelerator-based neutron irradiation facility for boron neutron capture therapy
A neutronic study of an accelerator-based neutron irradiation facility for boron neutron capture therapy
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用于硼中子捕获治疗的基于加速器的中子辐照设施的中子研究
DOI：
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发表时间：
1989
期刊：
影响因子：
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通讯作者：
R. Gahbauer
中科院分区：
文献类型：
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作者：
C. Wang;T. Blue;R. Gahbauer
利用三维蒙特卡罗输运计算，对用于硼中子俘获治疗（BNCT）的加速器中子辐照装置（ANIF）进行了中子学研究。ANIF的主要部件是一个射频四极质子加速器，一个/sup 7/Li靶和一个慢化剂组件。中子是通过用2.5 mev的质子轰击/sup 7/Li靶而产生的。从/sup 7/Li靶中产生的中子能量太大，不能用于BNCT，因此必须进行减速。计算表明，在所有的材料中，铍（BeO）和重水（D/sub 2/O）是最好的减速剂。其中，铍具有较好的中子能谱，而D/sub 2/O具有较高的中子强度。在D/sub 2/O中加入氧化铝（Al/sub 2/O/sub 3/）改善了中子能谱，但也增加了伽马射线污染。
A neutronic study of an accelerator-based neutron irradiation facility (ANIF) for boron neutron capture therapy (BNCT) was performed using three-dimensional Monte Carlo transport calculations. The major components of the ANIF are a radio-frequency quadrupole proton accelerator, a /sup 7/Li target, and a moderator assembly. Neutrons are generated by bombarding the /sup 7/Li target with 2.5-MeV protons. The neutrons emerging from the /sup 7/Li target are too energetic to be used for BNCT and must therefore be moderated. Calculations show that, among all materials for the ANIF, beryllia (BeO) and heavy water (D/sub 2/O) are the best moderators. Between them, beryllia provides better neutron spectra, but D/sub 2/O gives higher neutron intensities. Adding alumina (Al/sub 2/O/sub 3/) to D/sub 2/O improves the neutron spectra, but it also increases gamma-ray contamination.