Delayed absorption of macular edema accompanying serous retinal detachment after grid laser treatment in patients with branch retinal vein occlusion
Delayed absorption of macular edema accompanying serous retinal detachment after grid laser treatment in patients with branch retinal vein occlusion
复制标题
DOI：
10.1016/j.ophtha.2004.04.031
复制
发表时间：
2004-11-01
期刊：
影响因子：
13.7
通讯作者：
Takagi, H
中科院分区：
文献类型：
--
作者：
Ohashi, H;Oh, H;Takagi, H
目的：目的研究视网膜分支静脉阻塞（BRVO）患者格栅状激光光凝后黄斑水肿（ME）吸收的详细过程。预处理浆液性视网膜脱离（SRD）在中央凹对患者outcome.Design的影响也进行了评估：回顾性，干预性，比较cases series.Participants：37例BRVO患者提出了严重的ME.Methods：患者进行了治疗与网格激光光凝6个月的随访检查。基线和治疗后检查包括视力（VA）测量、荧光素血管造影和光学相干断层扫描（OCT）对ME的详细成像。黄斑厚度定义为从视网膜内表面到感觉视网膜外缘的距离（中央凹视网膜厚度）以及包括SRD在内的视网膜色素上皮的内缘主要结果测量：OCT治疗后黄斑厚度，VA转换为最小分辨率角的对数，以及SRD的吸收，结果：治疗后1、3、6个月黄斑中心凹高度和视力均较治疗前明显改善。总中心凹高度的降低和VA的增加之间也有显著的相关性。14只眼（37.8%）显示SRD，如基线时OCT所证实。在无SRD的眼中，中心凹视网膜厚度和VA以时间依赖的方式显著改善。然而，尽管SRD本身在治疗后6个月几乎被吸收，但与基线条件相比，治疗前SRD眼的VA和总中心凹高度的改善并不显著。结论：BRVO患者中心凹下SRD的存在阻碍了ME的吸收和格栅状激光光凝术后VA的恢复。(C)2004年，美国眼科学会。
Purpose: To study the detailed process of macular edema (ME) absorption after grid laser photocoagulation in patients with branch retinal vein occlusion (BRVO). The influence of pretreatment serous retinal detachment (SRD) at the fovea on patient outcome was also evaluated.Design: Retrospective, interventional, comparative case series.Participants: Thirty-seven BRVO patients presenting with severe ME.Methods: Patients were treated with grid laser photocoagulation with 6 months of follow-up examinations. Baseline and post-treatment examinations included measurements of visual acuity (VA), fluorescein angiography, and detailed imaging of ME by optical coherence tomography (OCT). Macular thickness was defined as the distance from the inner retinal surface to the outer border of the sensory retina (foveal retinal thickness) and also to the inner border of the retinal pigment epithelium including the SRD (total foveal elevation).Main Outcome Measures: Post-treatment macular thickness with OCT, VA converted to the logarithm of the minimum angle of resolution, and absorption of SRD, and correlations of macular thickness and VA both before and after treatment.Results: Total foveal elevation and VA were significantly improved at 1, 3, and 6 months after treatment. There was also a significant correlation between reduction of total foveal elevation and increase in VA. Fourteen eyes (37.8%) displayed SRD, as evidenced by OCT at the baseline. In eyes without SRD, foveal retinal thickness and VA had significantly improved in a time-dependent manner. However, although SRD itself was almost absorbed 6 months after treatment, the improvement of both VA and total foveal elevation in eyes with pretreatment SRD was not significant compared with baseline conditions. Both post-treatment total foveal elevation and VA of eyes with SRD tended to be worse than eyes without SRD.Conclusion: The presence of subfoveal SRD retards the absorption of ME and recovery of VA after grid laser photocoagulation in patients with BRVO. (C) 2004 by the American Academy of Ophthalmology.