MR autopsy in fetuses
MR autopsy in fetuses
复制标题
DOI：
10.1159/000048008
复制
发表时间：
2002-01-01
影响因子：
2.2
通讯作者：
Kubik-Huch, RA
中科院分区：
文献类型：
--
作者：
Huisman, TAGM;Wisser, J;Kubik-Huch, RA
目的：本研究的目的是确定死后磁共振成像（MR尸检）是否可以作为胎儿尸检的替代方法。MR尸检的产科管理的验证和风险咨询有关未来怀孕的价值进行了讨论。方法：10个连续的畸形胎儿在分娩后24小时内进行死后MRI检查。对所有胎儿进行产前超声检查。完整尸检作为金标准，结果。MR尸检证实了导致终止的每一项US诊断。所有MRI结果均经尸检证实。在两个胎儿中，尸检提供了与风险咨询相关的额外信息。组织学检查纠正了1例诊断。结论：MR尸检提供了以前只能从尸检中获得的有价值的信息。在拒绝围产期尸检的父母，磁共振尸检获得的信息可以用来验证产科管理和评估未来怀孕的风险。然而，尸检仍然是黄金标准。版权所有（C）2002 S. Karger AG，巴塞尔。
Objective: The purpose of this study was to determine whether postmortem magnetic resonance imaging (MR autopsy) could serve as an alternative to necropsy of fetuses. The value of MR autopsy in the validation of the obstetric management and in risk counseling concerning future pregnancies is discussed. Methods: 10 consecutive, malformed fetuses were examined by postmortem MRI within 24 h of delivery. Prenatal ultrasound (US) was performed in all fetuses. Complete necropsy served as gold standard, Results. MR autopsy confirmed every US diagnosis responsible for termination. All MRI findings were confirmed by necropsy. In two fetuses, necropsy gave additional information relevant for risk counseling. Histologic examination corrected the diagnosis in one case. Conclusions: MR autopsy provides valuable information previously only available from necropsy. In parents who refuse perinatal necropsy, the information obtained by MR autopsy can be used to validate obstetric management and to evaluate the risk for future pregnancies. Necropsy however remains the gold standard. Copyright (C) 2002 S. Karger AG, Basel.