Is the cerebellum important for podokinetic adaptation?
Is the cerebellum important for podokinetic adaptation?
复制标题
小脑对于足运动适应重要吗？
DOI：
10.1111/j.1749-6632.2002.tb07596.x
复制
发表时间：
2002
影响因子：
5.2
通讯作者：
Fletcher,WA
中科院分区：
文献类型：
--
作者：
Earhart,GM;Horak,FB;Jones,GMelvill;Block,EW;Weber,KD;Suchowersky,O;Fletcher,WA
在旋转的圆形跑步机上原地踏步一段时间后，当要求健康受试者在静止表面上原地踏步而没有视觉时，他们会无意中转身。[1]这种现象被称为足动后旋转（PKAR），代表了躯干相对于足部的旋转与空间中躯干旋转感知之间关系的重塑。我们研究了小脑在这种足动（PK）适应中的作用。鉴于小脑在许多运动学习任务中的作用，我们预期小脑损伤受试者的PK适应性受损。我们比较了受试者的能力，以适应旋转的行走表面，他们的能力，以适应投掷，而通过prismers.METHODSEight诊断小脑变性和/或脊髓小脑萎缩的受试者进行了比较，8个年龄匹配的控制。通过基因检测和/或MRI确认诊断。受试者完成一项基于Martin et al. 2设计的投掷任务。每个受试者站立，面对一个8× 8 cm的正方形目标，该目标放置在肩水平2 m处。每个受试者在戴上棱镜眼镜（30屈光度3 M压贴式菲涅耳透镜）前进行20次基线投掷，在戴上棱镜时进行40次适应投掷，在摘下棱镜后进行20次后适应投掷。在任务期间，每个球击中的位置都被标记并按顺序编号。在投掷任务之后，受试者暴露于PK刺激，该刺激包括在以45/s顺时针方向旋转的76 cm圆盘的轴上原地踏步15分钟。通过将节奏与固定在躯干上的节拍器相匹配，将步进频率保持在2 Hz。在15分钟的适应期之后，受试者在戴着眼罩和耳塞的情况下在固定圆盘的轴上进行30分钟的原地踏步。在这30分钟期间，通过旋转电位计记录PKAR响应。
BACKGROUNDAfter a period of stepping-in-place on a rotating circular treadmill, healthy subjects will inadvertently turn when asked to step-in-place without vision on a stationary surface. 1 This phenomenon, termed podokinetic after-rotation (PKAR), represents a remodeling of the relation between trunk rotation relative to the foot and the perception of trunk rotation in space. We investigated the role of the cerebellum in this podokinetic (PK) adaptation. Given the role of the cerebellum in many motor learning tasks, we expected subjects with cerebellar damage to show impaired PK adaptation. We compared subjects' ability to adapt to the rotating walking surface to their ability to adapt to throwing while looking through prisms.METHODSEight subjects with diagnoses of cerebellar degeneration and/or spinocerebellar atrophy were compared to eight age-matched controls. Diagnoses were confirmed by genetic testing and/or MRI. Subjects completed a throwing task based on the design of Martin et al. 2 Each subject stood facing an 8× 8 cm square target placed at shoulder level 2 m away. Each subject made 20 baseline throws before donning prism glasses (30 diopter 3M press-on Fresnel lens), 40 adaptation throws while wearing the prisms, and 20 postadaptation throws after doffing the prisms. The locations that each ball struck were marked and numbered sequentially during the task. After the throwing task, subjects were exposed to a PK stimulus that consisted of 15 minutes of stepping-in-place on the axis of a 76-cm disc rotating in a clockwise direction at 45/s. Stepping frequency was maintained at 2 Hz by matching cadence to a metronome affixed to the trunk. Following the 15-minute period of adaptation, subjects performed 30 minutes of stepping-in-place on the axis of the stationary disc while wearing a blindfold and earplugs. During this 30-minute period, PKAR responses were recorded by means of a rotational potentiometer.