Nutritional factors and Helicobacter pylori infection in Colombian children
Nutritional factors and Helicobacter pylori infection in Colombian children
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DOI：
10.1097/00005176-199711000-00004
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发表时间：
1997-11-01
影响因子：
2.9
通讯作者：
Collazos, T
中科院分区：
文献类型：
--
作者：
Goodman, KJ;Correa, P;Collazos, T
背景资料：幽门螺杆菌感染最常见于贫困人群，然而，对易感性的特定决定因素知之甚少。本报告描述了H.在哥伦比亚安第斯山脉的一个农村的儿童中，幽门螺杆菌感染和营养指标，在2至9岁的儿童中观察到69%的患病率。在对684名儿童（占哥伦比亚Aldana 2至9岁人口的92%）进行的一项横断面研究中，通过问卷调查获得了有关饮食因素的信息，通过直接测量获得了身高和体重，和H.幽门螺杆菌状态使用碳-13尿素呼气试验。多因素Logistic回归估计相对风险的营养indicators.Results：感染是最不常见的儿童谁吃几份水果和蔬菜，每天喝两杯或两杯以上的牛奶，并在上五分之一的身高为他们的年龄。与每天摄入三到五份水果和蔬菜的模式相比，每天摄入少于两份水果和蔬菜的儿童感染的几率增加了19倍（95%置信区间，4.0-91.9）。每天从水果和蔬菜中摄入维生素C少于40毫克的儿童感染的几率大大增加（比值比，7.2; 95%置信区间，1.5-34.1）与80-119 mg的模态摄入量相比; β-胡萝卜素的优势比为3.1（95%置信区间，1.2-7.9），与每日900 IU或以上的模式摄入量相比，每日摄入量低于300 IU。这项以人群为基础的研究结果表明，营养因素可能在决定对H。幽门感染(C)1997 Lippincott-Raven出版社。
Background: Helicobacter pylori infection occurs most frequently in impoverished populations; however, little is known about specific determinants of susceptibility. This report describes the relationship between H. pylori infection and nutritional indicators among children from a rural village in the Colombian Andes, where a prevalence of 69% was observed in children from 2 to 9 years old.Methods: In a cross-sectional study of 684 children, comprising 92% of the 2- to 9-year-old population of Aldana, Colombia, information was obtained on dietary factors by questionnaire, height and weight by direct measurement, and H. pylori status using the carbon-13 urea breath test. Multivariate logistic regression was used to estimate relative risks for nutritional indicators.Results: The infection was least frequent among children who ate several servings of fruits and vegetables daily, drank two or more cups of milk daily, and were in the upper quintile of height for their age. The odds of infection increased 19-fold (95% confidence interval, 4.0-91.9) among children who consumed less than two daily servings of fruits and vegetables compared with the modal intake of three to five daily servings. Children whose daily vitamin C intake from fruits and vegetables was less than 40 mg had greatly increased odds of infection (odds ratio, 7.2; 95% confidence interval, 1.5-34.1) compared to the modal intake of 80-119 mg; for beta-carotene, the odds ratio was 3.1 (95% confidence interval, 1.2-7.9) for intakes of less than 300 IU per day, compared with the modal daily intake of 900 IU or more.Conclusions: The results of this population-based study suggest that nutritional factors may play a role in determining susceptibility to H. pylori infection. (C) 1997 Lippincott-Raven Publishers.