Independence of firing correlates of anatomically proximate hippocampal pyramidal cells

Independence of firing correlates of anatomically proximate hippocampal pyramidal cells
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DOI:
10.1523/jneurosci.21-05-j0004.2001
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发表时间:
2001-03-01
影响因子:
5.3
通讯作者:
Barnes, CA
Barnes, CA
中科院分区:
医学1区
文献类型:
--
作者:
Redish, AD;Battaglia, FP;Barnes, CA

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在新皮质中,邻近的神经元经常表现出相关的编码特性。海马体中是否存在类似现象,目前存在相互矛盾的证据。为了定量评估这一点,对间隔 350-1400 微米的局部海马细胞组内部和之间的空间和时间放电相关性进行了比较。在超过 3000 个神经元的样本中没有发现聚类的证据。此外,在两种环境中活跃的细胞均匀地散布在
In neocortex, neighboring neurons frequently exhibit correlated encoding properties. There is conflicting evidence whether a similar phenomenon occurs in hippocampus. To assess this quantitatively, a comparison was made of the spatial and temporal firing correlations within and between local groups of hippocampal cells, spaced 350-1400 mum apart. No evidence of clustering was found in a sample of >3000 neurons. Moreover, cells active in two environments were uniformly interspersed at a scale of