Computational modeling and multilevel cancer control interventions.
Computational modeling and multilevel cancer control interventions.
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计算模型和多层次癌症控制干预措施。
DOI：
10.1093/jncimonographs/lgs014
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Mandelblatt,Jeanne
中科院分区：
文献类型：
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作者：
Morrissey,JosephP;Lich,KristenHassmiller;Price,RebeccaAnhang;Mandelblatt,Jeanne
本章概述了计算建模作为多层次癌症护理和干预研究的工具。基于模型的分析已经在各种“皮肤以下”或生物尺度以及各种“皮肤以上”或社会生态水平的癌症护理提供上进行。我们回顾了计算建模的基本要素，并说明了其在四个癌症控制干预领域的应用：烟草使用、结直肠癌筛查、宫颈癌筛查和乳腺癌治疗中的种族差异。这些模型大多只在一两个层面上研究了癌症的过程和结果。我们建议这些模型可以扩展到考虑涉及三个或更多层次的交互。展望未来，必须克服一些方法、结构和沟通障碍，以创建有用的多层次癌症干预和人口健康的计算模型。
This chapter presents an overview of computational modeling as a tool for multilevel cancer care and intervention research. Model-based analyses have been conducted at various “beneath the skin” or biological scales as well as at various “above the skin” or socioecological levels of cancer care delivery. We review the basic elements of computational modeling and illustrate its applications in four cancer control intervention areas: tobacco use, colorectal cancer screening, cervical cancer screening, and racial disparities in access to breast cancer care. Most of these models have examined cancer processes and outcomes at only one or two levels. We suggest ways these models can be expanded to consider interactions involving three or more levels. Looking forward, a number of methodological, structural, and communication barriers must be overcome to create useful computational models of multilevel cancer interventions and population health.