Gastric electric activity assessed by electrogastrography and gastric emptying scintigraphy in adolescents with eating disorders
Gastric electric activity assessed by electrogastrography and gastric emptying scintigraphy in adolescents with eating disorders
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DOI：
10.1097/00005176-200307000-00006
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发表时间：
2003-07-01
影响因子：
2.9
通讯作者：
Castro, M
中科院分区：
文献类型：
--
作者：
Diamanti, A;Bracci, F;Castro, M
背景：饮食失调患者可能会出现各种胃肠道症状，有时会导致食物摄入量减少和呕吐。作者分别通过胃电图和闪烁扫描评估患有饮食失调和消化不良症状的青少年患者是否改变了胃电活动和胃排空异常。方法：28 名患者（18 名厌食症患者和 10 名贪食症患者）和 16 名健康志愿者接受了胃电图检查； 28 名患者中的 20 名（14 名厌食症患者，6 名贪食症患者）接受了胃排空闪烁扫描。双极记录胃电图在标准进餐前后持续 1 小时 30 分钟。在胃排空闪烁扫描之前，患者禁食过夜；在测试过程中，他们摄入了带有锝-99m硫胶体标记的固体食物。使用 Wilcoxon 配对测试评估空腹与餐后胃电图变量的比率。使用Mann-Whitney检验来比较各组胃电图数据的绝对值。 Student配对t检验用于比较闪烁扫描结果，以60分钟胃排空百分比和胃排空时间（T1/2）表示。结果：贪食症患者在正常胃电活动和胃徐缓方面与厌食症患者和对照受试者存在显着差异，而与厌食症患者仅在胃快速性方面存在显着差异。这些胃电图变量在厌食症患者和对照受试者之间没有显着差异。贪食症患者的胃排空时间 (T-1/(2)) 明显长于厌食症患者。 结论：青少年有可记录的胃电活动和排空异常，而厌食症患者则没有，可能是因为其病程较短。 (C) 2003 年利平科特·威廉姆斯·威尔金斯公司
Background: Patients with eating disorders can refer to a variety of gastrointestinal symptoms, sometimes to justify reduced food intake and vomiting. The authors investigated whether adolescent patients with eating disorders and dyspeptic symptoms have altered gastric electric activity and abnormal gastric emptying as assessed respectively by electrogastrography and scintigraphy.Methods: Twenty-eight patients (18 with anorexia and 10 with bulimia) and 16 healthy volunteers underwent electrogastrography; 20 of the 28 patients (14 with anorexia and 6 with bulimia) underwent gastric emptying scintigraphy. Electrogastrography with bipolar recording lasted 1 hour, 30 minutes before and after a standard meal. Before gastric emptying scintigraphy, patients fasted overnight; during testing, they ingested a solid meal labeled with technetium-99m sulfur colloid. The ratio of fasting to postprandial electrogastrographic variables was evaluated using the Wilcoxon matched-pair test. The Mann-Whitney test was used to compare absolute values for electrogastrographic data in each group. The Student paired t test was used to compare scintigraphic results expressed as percentage of gastric emptying at 60 minutes and as the gastric emptying time (T1/2).Results: Patients with bulimia significantly differed from those with anorexia and control subjects regarding the amount of normal gastric electric activity and bradygastria, and from patients with anorexia only regarding tachygastria. These electrogastrographic variables did not differ significantly between patients with anorexia and control subjects. Gastric emptying time (T-1/(2)) was significantly longer in patients with bulimia than in those with anorexia.Conclusions: Adolescent have documentable abnormalities of gastric electric activity and emptying, whereas their counterparts with anorexia, probably owing to their shorter disease duration, do not. (C) 2003 Lippincott Williams Wilkins, Inc.