Quality of life following lung cancer surgery
Quality of life following lung cancer surgery
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DOI：
10.1136/thorax.58.3.194
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发表时间：
2003-03-01
期刊：
影响因子：
10
通讯作者：
Ståhle, E
中科院分区：
文献类型：
--
作者：
Myrdal, G;Valtysdottir, S;Ståhle, E
背景：非小细胞肺癌患者的生存期有限。因此，生活质量(QOL)是这类患者的一个重要问题。本研究的目的是评估肺癌患者开胸手术后的生活质量。方法：在瑞典乌普萨拉胸心血管外科的四年间(1997-2000)，194例肺癌患者接受了手术治疗，其中132例患者于2001年4月1日存活。这些患者接受了简明健康问卷(SF-36)、医院焦虑和抑郁(HAD)量表以及与肺部症状相关的特殊问题(应答率为85%)。接受冠状动脉搭桥术(CABG)的患者作为对照组(有效率91%)。结果：肺癌患者与冠脉搭桥术患者在SF-36(生理角色)中只有一个亚组不同，但其生活质量比健康对照组差。肺癌患者和冠脉搭桥术患者在焦虑方面没有差异，但后者更容易出现抑郁(5.0%vs3.0%)。目前吸烟者在心理健康维度的得分较低。结论：接受开放传统手术切除的肺癌患者的生活质量与冠脉搭桥术患者相当。肺癌患者由于肺功能下降而身体功能较差，但没有表现出焦虑或抑郁增加的迹象。那些在手术后继续吸烟的人损害了精神健康。
Background: Patients with non-small cell bronchogenic carcinoma have a limited survival. Quality of life (QoL) is therefore an issue of importance in this group of patients. The aim of the present study was to evaluate QoL in lung cancer patients after open surgery.Methods: During a 4 year period (1997-2000) 194 patients with primary bronchogenic carcinoma of the lung underwent surgery at the Department of Thoracic and Cardiovascular Surgery in Uppsala, Sweden; 132 patients were alive on 1 April 2001. These patients received the Short Form-36 (SF-36) health questionnaire, Hospital Anxiety and Depression (HAD) scale, and special questions related to pulmonary symptoms (response rate 85%). Patients who underwent coronary bypass surgery (CABG) served as a comparison group (response rate 91%). Corresponding estimates of QoL in healthy controls were obtained from the SF-36 manual for the Swedish population.Results: Lung cancer patients differed from CABG patients in only one subgroup of the SF-36 (role physical), but had poorer QoL than healthy controls. No difference in anxiety was found between the lung cancer patients and the CABG patients, but the latter were more likely to suffer from depression (5.0% v 3.0%). Current smokers scored lower in the mental health dimension assessment.Conclusion: Lung cancer patients who undergo open traditional surgical resection have a QoL comparable to that of CABG patients. Lung cancer patients have poorer physical function because of reduced pulmonary function, but show no sign of increased anxiety or depression. Those who continued to smoke after surgery had impaired mental health.