Measurement of post-operative cognitive dysfunction after cardiac surgery: a systematic review.
Measurement of post-operative cognitive dysfunction after cardiac surgery: a systematic review.
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DOI：
10.1111/j.1399-6576.2010.02236.x
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发表时间：
2010-07
影响因子：
2.1
通讯作者：
Marcantonio ER
中科院分区：
文献类型：
--
作者：
Rudolph JL;Schreiber KA;Culley DJ;McGlinchey RE;Crosby G;Levitsky S;Marcantonio ER
术后认知功能障碍（POCD）是一种认知功能较术前水平下降的症状，在心脏手术后经常被描述。本研究的目的是检验POCD的测量和定义的可变性。在电子医学文献数据库（EMBASE、MEDLINE、Psychinfo和护理及相关健康文献累积索引）中搜索搜索词的交集：“胸外科”和“认知、痴呆和神经心理测试”。摘要由2位审稿人独立审稿。我们对1995年以来发表的50多篇涉及心脏手术患者术前和术后心理测量测试的英文文章进行了全面回顾。对与POCD测量和定义有关的数据进行了摘录，并与1995年关于POCD测量的共识声明的建议进行了比较。在心脏手术患者中发现了62项关于POCD的研究。在这些研究中，只有不到一半的研究完成了推荐的神经心理学测试。最常测量的认知领域是注意力（n=56, 93%）和记忆（n=57, 95%）；运动技能的测量频率较低（n=36; 60%）。出现了POCD的四种定义：百分比下降（n=15）、标准偏差下降（n=14）、因素分析（n=13）和单个测试性能分析（n=12）。由于测量方法的差异，POCD的患病率在不同的研究中差异超过10倍。POCD的测量和定义有明显的可变性。这种异质性可能通过降低比较POCD病因和治疗研究的能力而阻碍进展。
Postoperative cognitive dysfunction (POCD) is a decline in cognitive function from preoperative levels, which has been frequently described after cardiac surgery. The purpose of this study was to examine the variability in measurement and definitions for POCD. Electronic medical literature databases (EMBASE, MEDLINE, Psychinfo, and Cumulative Index of Nursing and Allied Health Literature) were searched for the intersection of the search terms: “thoracic surgery” and “cognition, dementia, and neuropsychological test”. Abstracts were reviewed independently by 2 reviewers. English articles with more than 50 participants published since 1995 that performed preoperative and postoperative psychometric testing in patients undergoing cardiac surgery were reviewed in their entirety. Data relevant to the measurement and definition of POCD were abstracted and compared to the recommendations of a 1995 Consensus Statement on measurement of POCD. Sixty-two studies of POCD in patients undergoing cardiac surgery were identified. Of these studies, the recommended neuropsychological tests were done in less than half of the studies. Cognitive domains measured most frequently were attention (n=56; 93%) and memory (n=57; 95%); motor skills were measured less frequently (n=36; 60%). Four definitions of POCD emerged: percent decline (n=15), standard deviation decline (n=14), factor analysis (n=13), and analysis of performance on individual tests (n=12). Because of variability in its measurement, the prevalence of POCD varied by over 10-fold across studies. There is marked variability in the measurement and definition of POCD. This heterogeneity may impede progress by reducing the ability to compare studies about the causes and treatment of POCD.
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DOI：
10.1016/s0022-5223(95)70053-6
发表时间：
1995-11-01
影响因子：
6
作者：
GOLD, JP;CHARLSON, ME;ISOM, OW
通讯作者：
ISOM, OW
影响因子：
8.9
作者：
Cella, D;Bullinger, M;Barofsky, I
通讯作者：
Barofsky, I
影响因子：
4.6
作者：
BLUMENTHAL, JA;MAHANNA, EP;NEWMAN, MF
通讯作者：
NEWMAN, MF
影响因子：
8.3
作者：
Arrowsmith, JE;Harrison, MJG;Pugsley, WB
通讯作者：
Pugsley, WB
DOI：
10.1016/j.jtcvs.2005.08.057
发表时间：
2006-01-01
影响因子：
6
作者：
Hammon, JW;Stump, DA;Kon, ND
通讯作者：
Kon, ND