Prediction and validation of total and regional skeletal muscle volume by using B-mode ultrasonography in Japanese prepubertal children.
Prediction and validation of total and regional skeletal muscle volume by using B-mode ultrasonography in Japanese prepubertal children.
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使用 B 型超声检查日本青春期前儿童的总和局部骨骼肌体积的预测和验证。
DOI：
10.1017/s0007114511001103
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发表时间：
2015
影响因子：
3.6
通讯作者：
Sakamoto S.
中科院分区：
文献类型：
--
作者：
Midorikawa T;Ohta M;Hikihara Y;Torii S;Sakamoto S.
本研究的目的是开发基于回归的预测方程的脂肪量超声在日本儿童，并调查这些方程的有效性。共有127名6-12岁的健康日本青春期前儿童被随机分为两组：模型开发组（54名男孩和44名女孩）和验证组（18名男孩和11名女孩）。全身、躯干、手臂和腿部脂肪质量最初通过双能X射线吸收测定法（DXA，德尔菲A-QDR全身扫描仪; Hologic，Inc.，美国马萨诸塞州贝德福德）。然后，通过B型超声（5 MHz扫描头）在9个部位（手臂：前臂外侧、上臂前后;躯干：腹部和肩胛下;腿部：大腿前后、小腿前后）测量脂肪厚度。回归分析用于描述发育组中通过DXA和超声获得的部位匹配脂肪质量（全身、手臂、躯干和腿部）之间的关系。当这些脂肪量预测方程应用于验证组时，测量的总脂肪量和局部脂肪量与预测的脂肪量非常相似（平均差异计算为预测-测量的脂肪质量± 2 sd;男孩全身0.1（sd 0.5）kg，手臂0.1（sd 0.3）kg，躯干-0.1（sd 0.3）kg，腿部0.1（sd 0.5）kg;女孩全身0·5（sd 1·3）kg，手臂0·0（sd 0·3）kg，躯干0·1（sd 0·8）kg，腿部0·3（sd 0·6）kg），Bland-Altman分析未显示偏倚。这些结果表明，超声推导的男孩和女孩的预测方程是有用的估计总的和区域的脂肪量。
The present study was performed to develop regression-based prediction equations for fat mass by ultrasound in Japanese children and to investigate the validity of these equations. A total of 127 healthy Japanese pre-pubertal children aged 6–12 years were randomly separated into two groups: the model development group (fifty-four boys and forty-four girls) and the validation group (eighteen boys and eleven girls). Total body, trunk, arm and leg fat masses were initially determined by dual-energy X-ray absorptiometry (DXA, Delphi A-QDR whole-body scanner; Hologic, Inc., Bedford, MA, USA). Then, fat thickness was measured by B-mode ultrasound (5 MHz scanning head) at nine sites (arm: lateral forearm, anterior and posterior upper arm; trunk: abdomen and subscapular; leg: anterior and posterior thigh, anterior and posterior lower leg). Regression analyses were used to describe the relationships between the site-matched fat masses (total body, arm, trunk and leg) obtained by DXA and ultrasound in the development group. When these fat mass prediction equations were applied to the validation group, the measured total and regional fat mass was very similar to the predicted fat mass (mean difference calculated as predicted − measured fat mass ± 2 sd; total body 0·1 (sd 0·5) kg, arm 0·1 (sd 0·3) kg, trunk − 0·1 (sd 0·3) kg, leg 0·1 (sd 0·5) kg for boys; total body 0·5 (sd 1·3) kg, arm 0·0 (sd 0·3) kg, trunk 0·1 (sd 0·8) kg, leg 0·3 (sd 0·6) kg for girls), and the Bland–Altman analysis did not indicate a bias. These results suggest that ultrasound-derived prediction equations for boys and girls are useful for estimating total and regional fat mass.