Desire for children, difficulties achieving a pregnancy, and infertility distress 3 to 7 years after cancer diagnosis.
Desire for children, difficulties achieving a pregnancy, and infertility distress 3 to 7 years after cancer diagnosis.
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DOI：
10.1007/s00520-014-2279-z
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发表时间：
2014-10
影响因子：
3.1
通讯作者：
Lampic, Claudia
中科院分区：
文献类型：
--
作者：
Armuand, Gabriela M.;Wettergren, Lena;Rodriguez-Wallberg, Kenny A.;Lampic, Claudia
目的是调查生育年龄癌症治疗3至7年后幸存者对孩子的渴望、怀孕困难和不孕不育痛苦。癌症幸存者是在基于人口的国家癌症登记中确定的。符合条件的受试者在2003年至2007年期间被选为癌症诊断对象，年龄在18岁至45岁之间。向810名幸存者发送了一份邮寄问卷，其中包括研究特定问题、简短的36项健康调查和生育问题清单，484人参与(60%回答)。大多数对儿童有预治疗愿望的幸存者在治疗后3-7年仍想要孩子，这一群体的特点是年龄小，确诊时没有孩子。此外，相当数量的幸存者(n = 55，17%)对儿童没有预先治疗的愿望，但在治疗后改变了他们想要孩子的想法。在那些想要孩子的幸存者中，约有三分之一的人在接受癌症治疗后遇到了怀孕的困难，想要孩子的愿望得不到满足会导致心理健康状况变差。目前面临受孕困难的幸存者报告了中等程度的不孕不育痛苦，并对使用配子捐赠表示兴趣较低。从事癌症护理的卫生专业人员需要意识到，患者对未来孩子的计划可能会发生变化，特别是如果他们年轻且没有孩子的话。应向所有育龄患者提供关于癌症治疗对未来生育力和生育力保存的影响的充分信息。
The aim was to investigate desire for children, difficulties achieving a pregnancy, and infertility distress among survivors 3 to 7 years after cancer treatment in reproductive age. Cancer survivors were identified in national population-based cancer registries. Eligible subjects presented with selected cancer diagnoses between 2003 and 2007 between the ages of 18 to 45. A postal questionnaire including study-specific questions, the Short-Form 36 Health Survey and the Fertility Problem Inventory, was sent to 810 survivors, and 484 participated (60 % response). Most survivors who had a pretreatment desire for children still wanted children 3–7 years after treatment, and this group was characterized by young age and being childless at diagnosis. In addition, a substantial group of survivors (n = 55, 17 %) that did not have a pretreatment desire for children had changed their mind about wanting children after treatment. About a third of the survivors with a desire to have children had experienced difficulties achieving a pregnancy after the cancer treatment, and an unfulfilled desire to have children was associated with worse mental health. Survivors presently facing difficulties achieving a pregnancy reported moderate levels of infertility distress and expressed low interest in using gamete donation. Health professionals in cancer care need to be aware that patients’ plans for future children may change, particularly if they are young and childless. All patients of reproductive age should be provided with adequate information about the impact of cancer treatment on future fertility and fertility preservation.
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影响因子：
8.8
作者：
Peate, M.;Meiser, B.;Friedlander, M.
通讯作者：
Friedlander, M.
影响因子：
6.2
作者：
Letourneau JM;Ebbel EE;Katz PP;Katz A;Ai WZ;Chien AJ;Melisko ME;Cedars MI;Rosen MP
通讯作者：
Rosen MP
DOI：
10.1007/978-94-007-2492-1_1
发表时间：
2012-01-01
期刊：
REPRODUCTIVE HEALTH AND CANCER IN ADOLESCENTS AND YOUNG ADULTS
影响因子：
--
作者：
Rodriguez-Wallberg, Kenny A.
通讯作者：
Rodriguez-Wallberg, Kenny A.
影响因子：
6.1
作者：
Lampic, C;Svanberg, AS;Tydén, T
通讯作者：
Tydén, T
影响因子：
3.7
作者：
Carter, Jeanne;Raviv, Leigh;Barakat, Richard R.
通讯作者：
Barakat, Richard R.