Lung Dose Estimation of 222Rn and 220Rn Progeny Based on IMBA Professional® Software
Lung Dose Estimation of 222Rn and 220Rn Progeny Based on IMBA Professional® Software
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发表时间：
2020
影响因子：
5.9
通讯作者：
Jun Hu;K. Iwaoka;M. Hosoda;S. Tokonami
中科院分区：
文献类型：
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作者：
Jun Hu;K. Iwaoka;M. Hosoda;S. Tokonami
与222Rn（氡）和220Rn（钍射气）暴露相关的辐射剂量主要是由于吸入其短寿命的子体而不是气体。氡的剂量学数据通常用于评估氡诱发肺癌的风险，这些数据来自地下矿工的流行病学研究和居民汇总分析。为了估算氡子体和钍射气子体的肺剂量，需要剂量转换因子，即衰变产物的活度浓度或PAEC与剂量的比值。目前国内常用的三种剂量学软件RADEP、LUDEP和IMBA，可以胜任ICRP推荐的生物动力学和剂量学模型的推导，进而估算肺剂量。虽然三种内照射剂量学软件均采用ICRP推荐的剂量学模型，但由于数据处理技术的不同，内照射剂量的估算结果存在微小差异。虽然有一些研究者使用RADEP和LUDEP进行了氡和钍射气的肺剂量计算，但给出有效剂量系数的研究较少，尤其是IMBA。因此，在本研究中，根据ICRP 66和137提供的参考参数计算基于IMBA的剂量转换因子，并与RADEP和LUDEP的公布值进行比较。
Radiation doses associated with exposures to 222Rn (radon) and 220Rn (thoron) are primarily due to inhalation of their short-lived progeny instead of the gas. The dosimetric data of radon are commonly used to assess the risk of radon-induced lung cancer derived from epidemiological studies of underground miners and from residential pooled analyzes. For estimation of the lung dose due to radon and thoron progeny, the dose conversion factor, which is the ratio of the activity concentration or PAEC of the decay products and dose is needed. There are three commonly used internal dosimetric software RADEP, LUDEP, and IMBA, which can be competent to implement to most of the biokinetic and dosimetric models recommended by ICRP to deduce the dose conversion factor and moreover to estimate the lung dose. Although all of the three internal dosimetric software use the same dosimetric model recommended by ICRP, due to the different data handling techniques, there are minor differences between the estimation results of the internal dose. There were several researchers who used the RADEP and LUDEP to conduct the dose calculation of lung dose of radon and thoron, but fewer researches gave the effective dose coefficient especially on IMBA. In this research, therefore, the dose conversion factor based on IMBA was calculated based on the reference parameters provided by the ICRP 66 and 137 and was compared with the published value of RADEP and LUDEP.