Improved renal perfusion measurement with a dual navigator-gated Q2TIPS fair technique.
Improved renal perfusion measurement with a dual navigator-gated Q2TIPS fair technique.
复制标题
使用双导航器门控 Q2TIPS fair 技术改进了肾灌注测量。
DOI：
10.1002/mrm.22532
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发表时间：
2010
影响因子：
3.3
通讯作者：
Hillenbrand,ClaudiaM
中科院分区：
文献类型：
--
作者：
Song,Ruitian;Loeffler,RalfB;Hillenbrand,ClaudiaM
一种双导航门控、流量敏感交替反转恢复（FAIR）、稳定进动（true‐FISP）序列的真快速成像技术已被开发出来，用于肾脏灌注的精确定量。当呼吸运动导致反转切片远离成像切片时，FAIR方法通常会高估肾脏灌注，成像切片随后包含来自静态组织的未标记旋转。为了克服这一问题，引入了双导航方案来跟踪反演和成像切片，从而确保两个切片的位置相同。精确定义的丸长进一步提高了准确性，这是通过Q2TIPS的改进版本实现的（灌注定量成像使用单次减法，第二版本具有交错薄层ti1周期性饱和）：在反转后的特定时间将一系列饱和脉冲应用于成像切片的两侧。双导航门控技术在8名志愿者中进行了测试。肾皮质灌注率在191 ~ 378 mL/ 100g /min之间，平均为376 mL/ 100g /min。所提出的技术可能被证明最有利于幼儿和可能长时间屏住呼吸困难或被镇静/麻醉的患者的非对比造影肾灌注量化。Magn reason Med, 2010。©2010 Wiley‐Liss, Inc。
A dual navigator‐gated, flow‐sensitive alternating inversion recovery (FAIR) true fast imaging with steady precession (True‐FISP) sequence has been developed for accurate quantification of renal perfusion. FAIR methods typically overestimate renal perfusion when respiratory motion causes the inversion slice to move away from the imaging slice, which then incorporates unlabeled spins from static tissue. To overcome this issue, the dual navigator scheme was introduced to track inversion and imaging slices, and thus to ensure the same position for both slices. Accuracy was further improved by a well‐defined bolus length, which was achieved by a modification version of Q2TIPS (quantitative imaging of perfusion using a single subtraction, second version with interleaved thin‐slice TI1periodic saturation): a series of saturation pulses was applied to both sides of the imaging slice at a certain time after the inversion. The dual navigator‐gated technique was tested in eight volunteers. The measured renal cortex perfusion rates were between 191 and 378 mL/100 g/min in the renal cortex with a mean of 376 mL/100 g/min. The proposed technique may prove most beneficial for noncontrast‐based renal perfusion quantification in young children and patients who may have difficulty holding their breath for prolonged periods or are sedated/anesthetized. Magn Reson Med, 2010. © 2010 Wiley‐Liss, Inc.