Platinum-catalysed cinnamaldehyde hydrogenation in continuous flow
Platinum-catalysed cinnamaldehyde hydrogenation in continuous flow
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DOI：
10.1039/c5ra14984c
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发表时间：
2015-01-01
期刊：
影响因子：
3.9
通讯作者：
Lee, Adam F.
中科院分区：
文献类型：
--
作者：
Durndell, Lee J.;Wilson, Karen;Lee, Adam F.
铂是最广泛使用的加氢催化剂之一。在这里，我们描述了翻译的间歇反应连续流，提供可调的C=O与C=C氢化的Pt/SiO2催化剂，导致在高稳态活性和单程收率在选择性氢化肉桂醛肉桂醇在温和的条件下。由于从反应区去除了反应性形成的毒物，在延长流量操作下发生的催化剂失活可以忽略不计。工艺强化使肉桂醇的生产率提高了四倍。
Platinum is one of the most widely used hydrogenation catalysts. Here we describe the translation of batch reactions to continuous flow, affording tunable C=O versus C=C hydrogenation over a Pt/SiO2 catalyst, resulting in high steady state activity and single-pass yields in the selective hydrogenation of cinnamaldehyde to cinnamyl alcohol under mild conditions. Negligible catalyst deactivation occurs under extended flow operation due to removal of reactively-formed poisons from the reaction zone. Process intensification imparts a four-fold enhancement in cinnamyl alcohol productivity.