Assessment of sample pooling for SARS-CoV-2 molecular testing for screening of asymptomatic persons in Tunisia
Assessment of sample pooling for SARS-CoV-2 molecular testing for screening of asymptomatic persons in Tunisia
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DOI：
10.1016/j.diagmicrobio.2020.115125
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发表时间：
2020-11-01
影响因子：
2.9
通讯作者：
Boutiba-Ben Boubaker, Ilhem
中科院分区：
文献类型：
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作者：
Abid, Salma;Ferjani, Sana;Boutiba-Ben Boubaker, Ilhem
本研究的目的是测试RT-PCR检测的混合方法，以检测低病毒载量的SARS-CoV-2。我们发现，在多达10份样本池中仍可检出单个阳性标本。每个实验室应根据其具体情况对合并方案进行自己的评估和验证。(C)2020爱思唯尔公司All rights reserved.
The aim of this study is to test a pooling approach for the RT-PCR test to detect low viral loads of SARS-CoV-2. We found that a single positive specimen can still be detected in pools of up to 10. Each laboratory should conduct its own evaluation and validation of pooling protocols according to its specific context. (C) 2020 Elsevier Inc. All rights reserved.