Anterior nasal resistance in obese children with obstructive sleep apnea syndrome.
Anterior nasal resistance in obese children with obstructive sleep apnea syndrome.
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DOI：
10.1002/lary.24653
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发表时间：
2014-11
期刊：
影响因子：
2.6
通讯作者：
Arens, Raanan
中科院分区：
文献类型：
--
作者：
Sin, Sanghun;Wootton, David M.;McDonough, Joseph M.;Nandalike, Kiran;Arens, Raanan
为了评估伴有和不伴有OSAS的肥胖儿童的鼻阻力，使用呼吸暂停低通气指数（AHI）研究鼻阻力与OSAS严重程度的相关性，并检查性别和体重指数（BMI）与该测量的相关性。回顾性分析采用主动前鼻测压法测定潮汐呼吸时仰卧位清醒时鼻前阻力（aNR）。研究对象为30例肥胖OSAS患儿（年龄13.8±2.6岁，BMI-Z评分2.6±0.4）和32例匹配的肥胖对照组（年龄13.6±2.3岁，BMI-Z评分2.4±0.4）。进行非配对t检验和Spearman相关检验。OSAS组吸气（p=0.012）和呼气（p=0.003）时的aNR显著高于非OSAS组。OSAS组吸气aNR与AHI有显著相关性（r=0.39, p=0.04）。aNR与BMI-Z评分或性别无关。我们注意到，与肥胖对照组相比，肥胖OSAS患儿的aNR更高，吸气aNR与AHI显著相关。这些发现表明，高吸气aNR可能存在于表现为OSAS的肥胖儿童的因果或增强效应。
To evaluate nasal resistance in obese children with and without OSAS, study the correlation between nasal resistance and severity of OSAS using the apnea-hypopnea index (AHI), and examine the association of gender and body-mass index (BMI) with this measurement. Retrospective analysis Active anterior rhinomanometry was used to determine anterior nasal resistance (aNR) during wakefulness in the supine position during tidal breathing. Thirty obese children with OSAS (age 13.8±2.6 yrs, BMI-Z score 2.6±0.4) and 32 matched obese controls (age 13.6±2.3 yrs, BMI-Z score 2.4±0.4), were studied. Unpaired t-tests and Spearman correlation were performed. The OSAS group had significantly higher aNR than the non-OSAS group during inspiration (p=0.012) and expiration (p=0.003). A significant correlation between inspiratory aNR and AHI was found for the OSAS group (r=0.39, p=0.04). The aNR did not correlate with BMI-Z score or with either gender. We noted a higher aNR in obese children with OSAS as compared to obese controls and the aNR on inspiration correlated significantly with AHI. These findings suggest that a causal or augmentative effect of high inspiratory aNR may exist for obese children who exhibit OSAS.
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DOI：
10.1513/pats.200708-135mg
发表时间：
2008-02-15
期刊：
Proceedings of the American Thoracic Society
影响因子：
--
作者：
Lumeng, Julie C;Chervin, Ronald D
通讯作者：
Chervin, Ronald D
DOI：
10.1164/rccm.201008-1249oc
发表时间：
2011-03-15
影响因子：
24.7
作者：
Arens, Raanan;Sin, Sanghun;Shifteh, Keivan
通讯作者：
Shifteh, Keivan
影响因子：
1.5
作者：
Mitchell, Ron B.;Boss, Emily F.
通讯作者：
Boss, Emily F.
影响因子：
2.6
作者：
Tagaya, Mitsuhiko;Nakata, Seiichi;Nakashima, Tsutomu
通讯作者：
Nakashima, Tsutomu
影响因子：
3.4
作者：
Mitchell, RB;Kelly, J
通讯作者：
Kelly, J