Magnetic susceptibility and hardness of Au-xPt-yNb alloys for biomedical applications
Magnetic susceptibility and hardness of Au-xPt-yNb alloys for biomedical applications
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用于生物医学应用的 Au-xPt-yNb 合金的磁化率和硬度
DOI：
10.1016/j.actbio.2013.05.028
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发表时间：
2013
影响因子：
9.7
通讯作者：
Kenzo Asaoka
中科院分区：
文献类型：
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作者：
Emi Uyama;Shihoko Inui;Kenichi Hamada;Eiichi Honda;Kenzo Asaoka
人体内的金属器械在磁共振成像（MRI）中会产生严重的金属伪影。金属伪影主要由金属器械和人体组织之间的体积磁化率（χv）不匹配引起。在这项研究中，Au-xPt-yNb合金被开发用于制造MRI无伪影的生物医学金属器件。研究了这些合金的磁性能、硬度和相组成。Au-xPt-8 Nb合金显示出令人满意的χ v值。热处理没有明显改变Au-xPt-8 Nb合金的χ v值。这两种合金的维氏硬度（HV）远高于高铂合金;此外，在700 °C下时效提高了这两种合金的HV值。观察到由面心立方α1和α2相组成的双相结构，并且在700 °C时效促进相分离。Au-5 Pt-8 Nb和Au-10 Pt-8 Nb合金显示出令人满意的χ v值和高硬度，因此建议作为用于生物医学应用的MRI无伪影合金的候选物。
Metal devices in the human body induce serious metal artifacts in magnetic resonance imaging (MRI). Metals artifacts are mainly caused by a volume magnetic susceptibility (χv) mismatch between a metal device and human tissue. In this research, Au–xPt–yNb alloys were developed for fabricating MRI artifact-free biomedical metal devices. The magnetic properties, hardness and phase constitutions of these alloys were investigated. The Au–xPt–8Nb alloys showed satisfactoryχvvalues. Heat treatments did not clearly change theχvvalues for Au–xPt–8Nb alloys. The Vickers hardness (HV) of these two alloys was much higher than that of high-Pt alloys; moreover, aging at 700 °C increased the HV values of these two alloys. A dual phase structure consisting of face-centered cubic α1 and α2 phases was observed and aging at 700 °C promoted phase separation. The Au–5Pt–8Nb and Au–10Pt–8Nb alloys showed satisfactoryχvvalues and high hardness and are thus suggested as candidates for MRI artifact-free alloys for biomedical applications.