Differential effects of the retinopathy of prematurity exam on the physiology of premature infants.
Differential effects of the retinopathy of prematurity exam on the physiology of premature infants.
复制标题
早产儿视网膜病变检查对早产儿生理的不同影响。
DOI：
10.1038/s41372-019-0331-z
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发表时间：
2019
期刊：
影响因子：
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通讯作者：
Angeles,DanilynM
中科院分区：
文献类型：
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作者：
Tan,JohnBC;Dunbar,Jennifer;Hopper,Andrew;Wilson,ChristopherG;Angeles,DanilynM
目的比较早产儿视网膜病变（ROP）检查对有氧支持和无氧支持的早产儿生理的差异影响。研究设计我们收集了42名早产儿的数据（室内空气 = 19，氧支持 = 23），比较心率（HR）、全身外周饱和度（SpO2）、肠系膜组织氧饱和度（StO2）和临床事件（氧饱和度降低）等生理指标。结果我们发现检查期间和检查后短暂时间内的 HR 以及肠系膜 StO2、滴眼液给药期间、眼科检查期间以及检查后 8 分钟内的肠系膜 StO2 方面存在显着差异。在所有时间点，各组之间的 SpO2 均存在显着差异。与基线相比，接受氧气支持的婴儿在检查后胃残留量更高。结论接受氧气支持的早产儿可能因 ROP 检查而出现不良生理反应的风险更高。
ObjectiveTo compare the differential effects of the retinopathy of prematurity (ROP) examination on the physiology of premature infants with and without oxygen support.Study DesignWe collected data from 42 premature infants (room air = 19, oxygen support = 23) and compared physiological metrics including heart rate (HR), systemic peripheral saturation (SpO2), mesenteric tissue oxygen saturation (StO2) and clinical events (oxygen desaturation episodes, bradycardia events, and gastric residuals).ResultsWe found significant differences between groups in HR during and briefly after the exam, and in mesenteric StO2,during eye drop administration, eye exam, and up to 8 min after the exam. SpO2was significantly different between the groups at all time points. Gastric residuals were higher after the exam in infants on oxygen support, compared to baseline.ConclusionPremature infants on oxygen support may be at a higher risk of adverse physiologic effects in response to the ROP exam.