Aortic insufficiency associated with aortitis syndrome.
Aortic insufficiency associated with aortitis syndrome.
复制标题
主动脉瓣关闭不全与主动脉炎综合征相关。
DOI：
10.1536/ihj.8.107
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发表时间：
1967
期刊：
影响因子：
--
通讯作者：
S. Morooka
中科院分区：
文献类型：
--
作者：
H. Ueda;M. Sugiura;I. Ito;Y. Saito;S. Morooka
8年来44例主动脉瓣关闭不全综合征中有9例出现主动脉瓣关闭不全，发病率较高(20%)，未见文献报道。他们包括2男7女，年龄从21岁到68岁不等。两例发展为充血性心力衰竭的患者死亡。患肢血压缺乏主动脉瓣关闭不全的特征外周体征。胸部X线片显示心脏增大、升主动脉扩张和主动脉壁钙化。心电图显示左心室肥厚，心音图显示ERb‘s区舒张期减少杂音。逆行主动脉造影术显示升主动脉扩张。大动脉炎的分布至少包括受累于主动脉弓。对205例主动脉瓣关闭不全患者进行病因分类，发现主动脉炎综合征发病率高，居风湿性(112例)、梅毒(32例)、高血压(25例)之后，居第4位。并对大动脉炎综合征中主动脉瓣关闭不全的发生机制进行了讨论。主动脉瓣关闭不全在大动脉炎综合征患者中发生率较高，在其他类型的主动脉瓣关闭不全中高发，最后病理结果有力地表明，主动脉炎引起的主动脉环扩张累及升主动脉是导致主动脉瓣关闭不全的主要原因。
Aortic insufficiency was found in 9 of 44 cases of aortitis syndrome seen during 8 years, representing a high incidence (20%), unreported previously. They consisted of 2 men and 7 women, ranging in age from 21 to 68. Two cases which developed congestive heart failure died. Blood pressure in the diseased extremity lacked the characteristic peripheral signs of aortic insufficiency. X-ray films of the chest showed cardiac enlargement, dilatation of the ascending aorta and calcification of the aortic wall. Electrocardiogram showed left ventricular hypertrophy and phonocardiogram showed diastolic decreascendo murmur in the Erb's area. Retrograde aortography showed dilatation of the ascending aorta. Distribution of the aortitis included at least an involvement of aortic arch. Etiological classification of 205 cases of aortic insufficiency revealed unexpectedly high incidence of aortitis syndrome, which occupied the fourth place following rheumatic (112), syphilitic (32) and hypertensive (25) nature.Thirty-one similar cases were collected from the previous and the present reports and were reviewed.Pathology of the disease revealed dilatation of the ascending aorta, and destruction of the medial elastic fibers. Mechanism of producing aortic insufficiency in the aortitis syndrome was discussed. High incidence of aortic insufficiency among the cases of aortitis syndrome, frequent occurrence of aortic insufficiency in other types of aortitis and finally the pathological findings strongly indicated that dilatation of the aortic ring due to aortitis involving the ascending aorta is the primary cause of aortic insufficiency.