Proteolytic adaptor for transfer-messenger RNA-tagged proteins from α-proteobacteria

Proteolytic adaptor for transfer-messenger RNA-tagged proteins from α-proteobacteria
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DOI:
10.1128/jb.01387-06
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发表时间:
2007-01-01
影响因子:
3.2
通讯作者:
Keiler, Kenneth C.
Keiler, Kenneth C.
中科院分区:
生物学3区
文献类型:
--
作者:
Lessner, Faith H.;Venters, Bryan J.;Keiler, Kenneth C.

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我们已经在新月弯杆菌中确定了SspB的类似物,SspB是转移信使RNA(TmRNA)标记蛋白的蛋白水解适配器。Crescentus SspB与大肠杆菌SspB有有限的序列相似性,但在体外结合tmRNA标签,并在体内对标记蛋白的最佳蛋白质降解是必需的。
We have identified an analog of SspB, the proteolytic adaptor for transfer-messenger RNA (tmRNA)-tagged proteins, in Caulobacter crescentus. C. crescentus SspB shares limited sequence similarity with Escherichia coli SspB but binds the tmRNA tag in vitro and is required for optimal proteolysis of tagged proteins in vivo.