Surgical Resection of Pineal Epidermoid Cyst Contributed to Relieving Schizophrenia Symptoms
Surgical Resection of Pineal Epidermoid Cyst Contributed to Relieving Schizophrenia Symptoms
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手术切除松果体表皮样囊肿有助于缓解精神分裂症症状
DOI：
10.1016/j.wneu.2018.02.151
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发表时间：
2018
影响因子：
2
通讯作者：
Chen ZP
中科院分区：
文献类型：
--
作者：
Jiang Xiaobing;Chen Yinsheng;Zhou Zhihuan;Luo Liping;Wang Jian;Chen Zhongping;Hu Wanming;Zheng Huirong;Zhu Zhe;Wang J;Chen ZP
研究背景松果体已被证实与心境障碍和精神病性障碍的发生发展有关。然而，很少有研究着眼于松果体区肿瘤和精神疾病之间的关系。颅内表皮样囊肿通常发生在小脑脑桥角区，而在松果体区则极为罕见。松果体表皮样囊肿的情况下，精神分裂症从来没有被报道before.Case PresentationWe描述的情况下，一个23岁的男子谁提出到医院的症状暗示精神分裂症。在检查过程中，他被发现有松果体病变的脑磁共振成像。全切除肿瘤随后进行，病理证实表皮样囊肿。手术后一个月，患者的精神病症状显着改善免费的药物和完全恢复工作3个月postoperatives.ConclusionsThis情况下强调的重要性，包括质量病变的松果体区的精神障碍的鉴别诊断。它还提供了进一步的支持，松果体区可能在精神疾病的病理生理学中发挥作用，尽管需要更多的研究来阐明这种有趣的联系。
BackgroundThe pineal gland has been demonstrated to be involved in the development of mood and psychotic disorders. However, few studies have looked at the relationship between pineal region tumors and psychiatric disorders. Intracranial epidermoid cysts usually arise in the cerebellopontine angle area and are extremely rare in the pineal region. The case of pineal epidermoid cyst presenting as schizophrenia has never been reported before.Case PresentationWe described the case of a 23-year-old man who presented to the hospital with symptoms suggestive of schizophrenia. During work-up, he was found to have a pineal lesion on brain magnetic resonance imaging. Total resection of the tumor was subsequently performed, and pathology confirmed an epidermoid cyst. One month after surgery, the patient's psychotic symptoms significantly improved free of drug and fully returned to work 3 months postoperatively.ConclusionsThis case highlights the importance of including mass lesions of the pineal region in the differential diagnosis of psychotic disorders. It also provides further support that the pineal region may play a role in the pathophysiology of psychiatric diseases, although more studies will be needed to elucidate this interesting connection.