Prevalence of Painful Bladder Syndrome in Older Women

Prevalence of Painful Bladder Syndrome in Older Women
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DOI：
10.1016/j.urology.2008.01.053
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发表时间：
2009-03-01
期刊：
UROLOGY
影响因子：
2.1
通讯作者：
Curhan, Gary C.
Curhan, Gary C.
中科院分区：
医学4区
文献类型：
--
作者：
Lifford, Karen L.;Curhan, Gary C.

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目的：利用护士健康研究（NHS）队列研究老年妇女中膀胱疼痛综合征（PBS）的患病率和相关症状。方法2004年，NHS参与者通过邮寄问卷的方式被问及：“在过去的10年里，你是否经历过膀胱或盆腔疼痛，并伴有泌尿系统症状，连续3个月以上？”回答“是”的女性会收到一份详细的补充问卷。根据前6个月的症状和烦恼信息计算严重程度评分。结果67,095名参与者回答了PBS筛选问题。对所有4005名回答“是”的女性发送了一份补充问卷，其中3042名（76%）做出了回应。1548名应答者（51%）报告了与PBS相符的症状，占筛查队列的2.3%。65岁以下女性的PBS患病率为1.7%，80岁及以上女性的PBS患病率逐渐上升至4.0% （P趋势< 0.001）。严重程度，基于症状和困扰，14.8%的PBS女性为轻度，29.0%为中度，56.2%为重度。结论膀胱疼痛综合征是女性的常见病。PBS的患病率随着年龄的增长而增加，绝大多数患有PBS的妇女有中度或重度症状。中华泌尿外科杂志（英文版），2009。(C) 2009爱思唯尔公司
OBJECTIVES To examine the prevalence of and symptoms associated with painful bladder syndrome (PBS) in a population of older women, utilizing the Nurses' Health Study (NHS) cohort.METHODS In 2004, NHS participants were asked by mailed questionnaire, "In the past 10 years, have you experienced bladder or pelvic pain associated with urinary symptoms for more than 3 consecutive months?" Women who responded "yes" were sent a detailed supplementary questionnaire. A severity score was calculated according to information about symptoms and bother in the previous 6 months.RESULTS The PBS screening question was answered by 67,095 participants. A supplemental questionnaire was sent to all 4005 women who answered yes, and 3042 (76%) responded. Symptoms consistent with PBS were reported by 1548 respondents (51%), representing 2.3% of the screened cohort. The prevalence of PBS was 1.7% in those younger than 65 years and increased progressively to 4.0% in women aged 80 years and older (P trend < 0.001). Severity, based on both symptoms and bother, was mild in 14.8% of women with PBS, moderate in 29.0%, and severe in 56.2%.CONCLUSIONS Painful bladder syndrome is a common condition in women. The prevalence of PBS increases with age, and the vast majority of women with PBS have moderate or severe symptoms. UROLOGY 73: 494-498, 2009. (C) 2009 Elsevier Inc.