CT Features and Short-term Prognosis of COVID-19 Pneumonia: A Single-Center Study from Kashan, Iran

CT Features and Short-term Prognosis of COVID-19 Pneumonia: A Single-Center Study from Kashan, Iran
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DOI:
10.1148/ryct.2020200130
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发表时间:
2020-04-01
期刊:
RADIOLOGY-CARDIOTHORACIC IMAGING
影响因子:
--
通讯作者:
Rajebi, Hamid
Rajebi, Hamid
中科院分区:
其他
文献类型:
--
作者:
Tabatabaei, Seyed Mohammad Hossein;Talari, Hamidreza;Rajebi, Hamid

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目的:探讨2019冠状病毒病(COVID-19)确诊患者的某些CT胸部特征是否具有短期预后价值。材料与方法:选取120例连续行胸部CT的有症状COVID-19感染患者为研究对象。患者分为三组:常规住院、重症监护病房住院和基于短期随访的死亡。记录详细的初始CT特征和分布评价。结果:死亡组患者平均年龄70.7岁,显著高于其他两组(P, 0.05)。94%(113/120)患者有磨玻璃混浊(GGO)。大多数患者存在外周区和下区偏爱。胸膜下保留和胸腔积液分别见于约23%(28/120)和17%(20/120)的患者。与常规住院患者相比,联合重症监护室组和死亡患者有明显更多的实变、空气支气管征、疯狂铺路和肺部中央受累(均P, 0.05)。结论:本研究支持了先前描述的具有双侧GGO的COVID-19肺炎的典型CT表现,其外周分布和下肺区优先。胸膜下保留和胸腔积液分别约占COVID-19患者的五分之一和六分之一。CT胸部初发实变、支气管充气征、肺中央受累、疯狂铺装、胸腔积液具有潜在的预后价值,多见于危重患者。
Purpose: To assess whether certain CT chest features of patients with confirmed coronavirus disease 2019 (COVID-19) may have short-term prognostic value.Materials and Methods: One hundred-twenty consecutive symptomatic patients with COVID-19 infection who had undergone chest CT were enrolled in this retrospective study. Patients were categorized into three groups: routine inward hospitalization, intensive care unit admission, and deceased based on a short-term follow-up. Detailed initial CT features and distributional evaluation were recorded.Results: The mean age in the deceased group was 70.7 years, significantly higher than the other two groups (P,.05). Ninety-four percent (113/120) of the patients had ground-glass opacities (GGO). Peripheral and lower zone predilection was present in most patients. Subpleural sparing and pleural effusion were seen in approximately 23% (28/120) and 17% (20/120) of the patients, respectively. The combined intensive care unit group and deceased patients had significantly more consolidation, air bronchograms, crazy paving, and central involvement of the lungs compared with routinely hospitalized patients (all P,.05).Conclusion: This study supports the previously described typical CT appearance of COVID-19 pneumonia with bilateral GGO, in peripheral distribution and lower lung zone predilection. Subpleural sparing and pleural effusion were seen approximately in one-fifth and one-sixth of the patients with COVID-19, respectively. Consolidation, air bronchograms, central lung involvement, crazy paving and pleural effusion on initial CT chest have potential prognostic values, the features more commonly observed in critically ill patients.