Toward the ultimate metal microelectrode
Toward the ultimate metal microelectrode
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DOI：
10.1016/0165-0270(95)00107-7
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发表时间：
1995-12-01
影响因子：
3
通讯作者：
Martyniuk, J
中科院分区：
文献类型：
--
作者：
Loeb, GE;Peck, RA;Martyniuk, J
金属微电极刺激和记录神经元动作电位的性能取决于其几何、电学和力学性能的精确控制。我们描述了一种材料的组合，其特性接近可实现性能的基本物理限制和可重复的制造技术，可以提供非常小尺寸的探针。纯铱线经电解磨尖，用聚苯乙烯-c绝缘蒸汽涂层，并使用自动可控紫外激光暴露尖端。铱的电化学活化增加了金属-电解质界面的电容，使得相关频段（100-10 000 Hz）的整体阻抗由周围组织的接入电阻主导。
The performance of metal microelectrodes for stimulating and recording neuronal action potentials depends on precise control of their geometrical, electrical and mechanical properties. We describe a combination of materials whose properties approach fundamental physical limitations on achievable performance and reproducible fabrication techniques that provide probes with very small dimensions. Pure iridium wire is electrolytically sharpened, vapor-coated with Parylene-C insulation and the tip exposed using an automatically steerable UV laser. Electrochemical activation of the iridium increases the capacitance of the metal-electrolyte interface so that the overall impedance in the relevant frequency band (100-10 000 Hz) is dominated by the access resistance of the surrounding tissues.