Integrating tobacco treatment into lung cancer screening practices: Study protocol for the Screen ASSIST randomized clinical trial.
Integrating tobacco treatment into lung cancer screening practices: Study protocol for the Screen ASSIST randomized clinical trial.
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DOI：
10.1016/j.cct.2021.106586
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发表时间：
2021-12
影响因子：
2.2
通讯作者：
Rigotti NA
中科院分区：
文献类型：
--
作者：
Neil JM;Marotta C;Gonzalez I;Chang Y;Levy DE;Wint A;Harris K;Hawari S;Noonan E;Styklunas G;Crute S;Howard SE;Sheppard J;Lennes IT;Jacobson F;Flores EJ;Haas JS;Park ER;Rigotti NA
将烟草治疗服务整合到肺癌筛查(LCS)中，有可能利用一个“有教益的时刻”促进长期吸烟者戒烟，并减少获得烟草治疗的差距。本议定书文件描述了筛查辅助(协助筛查支持停止烟草)试验，该试验将确定如何在LCS的背景下最好地提供循证烟草治疗。Screen Assistate是一项随机临床试验，采用3因素完全交叉析因设计，将计划参加麻省总医院Brigham医疗系统多个地点的LCS的当前吸烟者(过去30天内任何香烟使用情况)纳入其中。为了最大限度地扩大影响范围，招聘在3个时间点进行：1)在LCS日程安排时，2)在LCS访问时，以及3)参与者收到LCS结果之后。参与者按LCS研究地点和招募地点进行分层，并随机分配到8组，测试干预成分在远程健康咨询持续时间(4周与8周)、尼古丁替代疗法持续时间(2周与8周)以及通过名为AuntBertha的服务(转诊与不转诊)对健康的社会决定因素进行系统筛选和转介方面的不同。主要的研究结果是在6个月的随访中自我报告过去7天的戒烟情况。这项试验还将评估系统集成和评估干预措施的实施情况。Screen Assistant将在长期重度吸烟者的情况下确定最有效的戒烟治疗组合，以提高长期重度吸烟者的长期戒烟治疗的成本效益和生活质量。
Integrating tobacco treatment services into lung cancer screening (LCS) has the potential to leverage a ‘teachable moment’ to promote cessation among long-term smokers and reduce disparities in tobacco treatment access. This protocol paper describes the Screen ASSIST (Aiding Screening Support In Stopping Tobacco) trial, which will identify how to best deliver evidence-driven tobacco treatment in the context of LCS. Screen ASSIST is a randomized clinical trial with a 3-factor, fully crossed factorial design that enrolls current smokers (any cigarette use in the past 30 days) scheduled to attend LCS at multiple sites in the Mass General Brigham healthcare system. To maximize reach, recruitment is conducted at 3 time points: 1) at the time of LCS scheduling, 2) at the LCS visit, and 3) after the participant has received their LCS results. Participants are stratified by LCS study site and recruitment point and randomly assigned into 8 groups that test intervention components varying on telehealth counseling duration (4 weeks vs. 8 weeks), nicotine replacement therapy duration (2 weeks vs. 8 weeks), and systematic screening and referral for social determinants of health via a service named ‘AuntBertha’ (referral vs. no referral). The primary study outcome is self-reported past 7-day tobacco abstinence at 6-month follow-up. This trial will also assess systems integration and evaluate implementation of the intervention. Screen ASSIST will identify the most effective combination of tobacco cessation treatments within the LCS context, in order to improve the cost-effectiveness of LCS and quality of life among long-term heavy smokers.
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影响因子：
12.7
作者：
Glasgow, RE;Vogt, TM;Boles, SM
通讯作者：
Boles, SM
影响因子：
13.8
作者：
Drouin O;Sato R;Drehmer JE;Nabi-Burza E;Hipple Walters B;Winickoff JP;Levy DE
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作者：
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Nichter, Mark