Toward a Definition of Sarcopenia
Toward a Definition of Sarcopenia
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DOI：
10.1016/j.cger.2011.04.001
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发表时间：
2011-08-01
影响因子：
3.3
通讯作者：
Rolland, Yves
中科院分区：
文献类型：
--
作者：
Cederholm, Tommy E.;Bauer, Juergen M.;Rolland, Yves
骨质疏松症的定义已经被科学利益相关者和行业代表彻底讨论，以增加这一概念的临床适用性。最近的5个平行过程中的3个(其中2个尚待解决)汇集的共识是，骨质疏松症主要但不仅是一种年龄相关的疾病，其定义是肌肉质量和肌肉功能的共同存在。导致骨质疏松症的因素包括衰老、慢性病、缺乏体力活动和食物摄入量不足。恶病质可被认为是加速肉质减少的一种病因途径。石棺减少症的调整和扩展定义促进了这一概念的临床应用。
The definition of sarcopenia has been thoroughly discussed by scientific stakeholders and industry representatives to increase the clinical applicability of the concept. The pooled consensus from 3 of 5 recent and parallel processes, of which 2 are pending, is that sarcopenia is mainly, but not only, an age-related condition defined by the combined presence of reduced muscle mass and muscle function. Contributing factors to sarcopenia are senescence, chronic disease, physical inactivity, and poor food intake. Cachexia may be considered as one etiologic pathway of an accelerated sarcopenia. The adjusted and extended definitions of sarcopenia promote the clinical use of the concept.