Body mass index in young men and the risk of subsequent knee and hip osteoarthritis
Body mass index in young men and the risk of subsequent knee and hip osteoarthritis
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DOI：
10.1016/s0002-9343(99)00292-2
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发表时间：
1999-12-01
影响因子：
5.9
通讯作者：
Klag, MJ
中科院分区：
文献类型：
--
作者：
Gelber, AC;Hochberg, MC;Klag, MJ
中年肥胖与晚年膝关节骨关节炎风险增加有关。我们试图确定是否在年轻男性的身体质量指数是一个危险因素，为随后的发展膝关节和髋关节骨关节炎的subjecTS和METHODS：身体质量指数进行了评估，1,180名男性医学生在23 +/- 2（平均值+/- SD）年，并在几次随访期间。膝关节和髋关节骨关节炎的发病率被确定的自我报告和证实的信息症状和放射学findings.Results：在中位随访36年，62名参与者开发膝关节骨关节炎和27髋关节骨关节炎。膝关节骨关节炎的发病率与20 - 29岁和30 - 39岁的体重指数密切相关（均P
PURPOSE: Obesity in middle age is associated with an increased risk of osteoarthritis of the knees in later life. We sought to determine whether body mass index in young men was a risk factor for the subsequent development of osteoarthritis of the knee and hip.SUBJECTS AND METHODS: Body mass index was assessed in 1,180 male medical students at age 23 +/- 2 (mean +/- SD) years and at several times during follow-up. The incidence of knee and hip osteoarthritis was ascertained by self-report and corroborated with information on symptoms and radiographic findings.RESULTS: During a median follow-up of 36 years, 62 participants developed knee osteoarthritis and 27 developed hip osteoarthritis. The incidence of knee, but not hip, osteoarthritis was strongly associated with body mass index assessed at ages 20 to 29 pears and 30 to 39 years (both P