Eyeblink conditioning and systems consolidation: An ironic yet powerful pairing
Eyeblink conditioning and systems consolidation: An ironic yet powerful pairing
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DOI：
10.1016/j.nlm.2010.12.003
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发表时间：
2011-02-01
影响因子：
2.7
通讯作者：
Clark, Robert E.
中科院分区：
文献类型：
--
作者：
Clark, Robert E.
系统整合涉及一个漫长的记忆重组过程，这似乎与陈述性记忆明显相关。陈述性记忆可以与简单的延迟眨眼经典条件反射形成鲜明对比，后者是非陈述性记忆的典型例子。然而，在条件刺激和非条件刺激之间插入一个轨迹间隔赋予了眨眼（轨迹）条件反射许多陈述性记忆的特征。在人类身上的研究已经证实，痕迹条件反射需要陈述性记忆。近年来，动物的眨眼条件反射已成为研究系统整合的最有力的方法之一。因此，具有讽刺意味的是，一种基本上非陈述性的记忆形式在陈述性记忆的组织方面如此具有指导意义。爱思唯尔公司出版
Systems consolidation involves a prolonged process of memory reorganization that appears to be distinctly related to declarative memory. Declarative memory can be sharply contrasted with simple delay eyeblink classical conditioning, a prototypical example of nondeclarative memory. Yet inserting a trace interval between the conditioned and unconditioned stimuli endows eyeblink (trace) conditioning with many features of declarative memory. Work in humans has established that trace conditioning requires declarative memory. Recently trace eyeblink conditioning in animals has become one of the most powerful methods to study systems consolidation. Thus, it is ironic that a substantially nondeclarative form of memory has been so instructive concerning the organization of declarative memory. Published by Elsevier Inc.