Epidemiologic study of physiological effects in usual and volunteer citrus workers from organophosphate pesticide residues at reentry.
Epidemiologic study of physiological effects in usual and volunteer citrus workers from organophosphate pesticide residues at reentry.
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返回时有机磷农药残留对普通柑橘工人和志愿柑橘工人生理影响的流行病学研究。
DOI：
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发表时间：
1981
期刊：
影响因子：
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通讯作者：
W. Kilgore
中科院分区：
文献类型：
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作者：
J. Kraus;R. Mull;P. Kurtz;W. Winterlin;C. Franti;N. Borhani;W. Kilgore
在一项柑橘收获机的研究中，评估了与有机磷（OP）农药暴露相关的生物学参数。研究了胆碱酯酶抑制剂农药环境残留对这些参数的影响。此外，还确定了普通工人和志愿工人在田间作业期间接触农药残留后的生化参数是否不同。普通农场工人的尿液代谢物结果表明，发生了一些接触OP农药的情况。太少的工人可在现场研究的再入阶段，以评估这种暴露对血液胆碱酯酶的影响。基线（非接触）乙酰胆碱酯酶（AChE）和血浆胆碱酯酶（PCHE）的活动显着高于通常（墨西哥裔美国人）的工人比志愿者（学生志愿者）。在测试柑橘格罗夫的学生志愿者显示，在接触期间PCHE的统计学显着下降，但乙酰胆碱酯酶活性，尿液代谢产物和残留水平的变化非常小。这些研究结果的影响进行了讨论，根据目前的再入标准，以及未来的流行病学研究再入研究。
Biological parameters associated with organophosphate (OP) pesticide exposure were evaluated in a study of citrus harvesters. Changes in these parameters related to environmental residues of cholinesterase (ChE) inhibiting pesticides were studied. Further, it was determined whether usual and volunteer workers differed in their biochemical parameters after exposure to pesticide residues during field operations. Urine metabolite findings for usual farm workers showed that some exposure to OP pesticides had occurred. Too few workers were available during the reentry stage of the field study to evaluate the effect of this exposure on blood ChE. Baseline (nonexposure) acetylcholinesterase (AChE) and plasma cholinesterase (PChE) activities were significantly higher in usual (Mexican American) workers than in volunteer workers (student volunteers). Student volunteers in the test citrus grove showed statistically significant declines in PChE during the exposure period, yet changes in AChE activity, urine metabolites, and residue levels were very small. The implications of these findings are discussed in light of current reentry standards as well as future epidemiologic studies on reentry research.