Sex specificity of ventral anterior Cingulate cortex suppression during a cognitive task
Sex specificity of ventral anterior Cingulate cortex suppression during a cognitive task
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DOI：
10.1002/hbm.20340
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发表时间：
2007-11-01
影响因子：
4.8
通讯作者：
Silbersweig, David
中科院分区：
文献类型：
--
作者：
Butler, Tracy;Imperato-McGinley, Julianne;Silbersweig, David
腹侧前扣带皮层 (vACC) 是一个高度互连的大脑区域，被认为反映了认知和情感有时相互竞争的需求。 vACC 和背侧 ACC (dACC) 之间的相互关系可能在维持认知和情绪处理之间的平衡中发挥作用。将功能性 MRI 与认知要求较高的视觉空间任务（心理旋转）结合使用，我们发现只有女性表现出 vACC 抑制和与 dACC 的反向功能连接。 vACC 功能的性别差异（之前在消极情绪条件下描述过）在这里扩展到了认知方面。考虑参与者的性别对于理解 vACC 在认知和情感处理中的作用至关重要。
Ventral anterior cingulate cortex (vACC) is a highly interconnected brain region considered to reflect the sometimes competing demands of cognition and emotion. A reciprocal relationship between vACC and dorsal ACC (dACC) may play a role in maintaining this balance between cognitive and emotional processing. Using functional MRI in association with a cognitively-demanding visuospatial task (mental rotation), we found that only women demonstrated vACC suppression and inverse functional connectivity with dACC. Sex differences in vACC functioning-previously described under conditions of negative emotion-are extended here to cognition. Consideration of participant sex is essential to understanding the role of vACC in cognitive and emotional processing.