Perturbation of chromatin architecture on ecdysterone induction of Drosophila melanogaster small heat shock protein genes.
Perturbation of chromatin architecture on ecdysterone induction of Drosophila melanogaster small heat shock protein genes.
复制标题
染色质结构的扰动对果蝇小热休克蛋白基因蜕皮甾酮诱导的影响。
DOI：
10.1128/mcb.9.1.332-335.1989
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发表时间：
1989
影响因子：
5.3
通讯作者：
Cartwright,IL
中科院分区：
文献类型：
--
作者：
Kelly,SE;Cartwright,IL
在果蝇小热休克蛋白基因的蜕皮甾酮刺激转录中观察到 DNase I 超敏性模式的改变。在 hsp27 和 hsp22 附近诱导扰动，同时在 hsp23 和发育调控基因 1 之间的基因间区域中染色质展开的广泛结构域。这些区域代表了蜕皮甾酮调控相互作用的候选区域。
Alterations in the pattern of DNase I hypersensitivity were observed on ecdysterone-stimulated transcription ofDrosophila melanogastersmall heat shock protein genes. Perturbations were induced nearhsp27andhsp22, coupled with an extensive domain of chromatin unfolding in the intergenic region betweenhsp23and the developmentally regulated gene 1. These regions represent candidates for ecdysterone regulatory interactions.