Resonant tectorial membrane motion in the inner ear: Its crucial role in frequency tuning
Resonant tectorial membrane motion in the inner ear: Its crucial role in frequency tuning
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DOI：
10.1073/pnas.93.16.8727
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发表时间：
1996-08-06
影响因子：
11.1
通讯作者：
Zenner, HP
中科院分区：
文献类型：
--
作者：
Gummer, AW;Hemmert, W;Zenner, HP
长期以来，人们一直认为盖膜在耳蜗的灵敏度中起着重要作用。特别地，已经提出，除了基底膜的共振系统之外，盖膜提供第二共振系统，其有助于耳蜗分区的运动的放大。到目前为止，技术上的困难阻碍了对覆膜的振动测量，因此，排除了机械共振的直接证据。在本文报道的研究中，通过使用一种将激光干涉测量与光电二极管技术相结合的新方法，在两个正交方向上测量覆膜的振动，实验表明，顶盖膜的运动是共振的，其频率比基底膜的共振频率低0.5倍频程（oct），并且平行于网状板极化，结果表明，顶盖膜的共振运动是由于顶盖膜的质量与外毛细胞静纤毛的顺应性之间的平行共振，并结合外毛细胞的收缩力，提出了盖膜的惯性运动提供了允许机械能正反馈到耳蜗分区中的必要条件，从而放大和调谐耳蜗响应。
The tectorial membrane has long been postulated as playing a role in the exquisite sensitivity of the cochlea. In particular, it has been proposed that the tectorial membrane provides a second resonant system, in addition to that of the basilar membrane, which contributes to the amplification of the motion of the cochlear partition. Until now, technical difficulties had prevented vibration measurements of the tectorial membrane and, therefore, precluded direct evidence of a mechanical resonance, In the study reported here, the vibration of the tectorial membrane was measured in two orthogonal directions by using a novel method of combining laser interferometry with a photodiode technique, It is shown experimentally that the motion of the tectorial membrane is resonant at a frequency of 0.5 octave (oct) below the resonant frequency of the basilar membrane and polarized parallel to the reticular lamina, It is concluded that the resonant motion of the tectorial membrane is due to a parallel resonance between the mass of the tectorial membrane and the compliance of the stereocilia of the outer hair cells, Moreover, in combination with the contractile force of outer hair cells, it is proposed that inertial motion of the tectorial membrane provides the necessary conditions to allow positive feedback of mechanical energy into the cochlear partition, thereby amplifying and tuning the cochlear response.