Electrophysiological studies of human face perception. I: Potentials generated in occipitotemporal cortex by face and non-face stimuli
Electrophysiological studies of human face perception. I: Potentials generated in occipitotemporal cortex by face and non-face stimuli
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DOI：
10.1093/cercor/9.5.415
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发表时间：
1999-07-01
期刊：
影响因子：
3.7
通讯作者：
McCarthy, G
中科院分区：
文献类型：
--
作者：
Allison, T;Puce, A;McCarthy, G
本文和接下来的两篇论文描述了 98 名患者的视觉刺激诱发的事件相关电位 (ERP)，这些患者将电极直接放置在皮质表面上以监测医学上难治性癫痫发作。患者观看面孔、乱序面孔、字母串、数字串以及有生命和无生命物体的图片。本文描述了纹状体和纹状体周皮层中产生的 ERP，这些 ERP 由面部诱发，以及由正弦光栅、物体和字母串诱发。纹状体和纹状体周皮层产生的短潜伏期 ERP 对亮度等基本刺激特征敏感。发现了三种类型的面部特异性 ERP：（i）从腹侧枕颞皮层记录的峰值潜伏期约为 200 ms（N200）的表面负电位，（ii）主要从颞中回记录的外侧表面 N200，以及（iii）从后腹侧枕颞、后外侧颞叶和前腹侧颞叶皮层记录的晚期正电位（P350）。脸部特定的 N200 之前是 P150，之后是 P290 和 N700 ERP。 N200 反映最初的面部特定处理，而 P290、N700 和 P350 反映在 N200 部位或附近以及前腹侧颞叶皮层中的后期面部处理。面部特异性 N200 振幅在男性和女性、正常和异常半球、或左右半球中没有显着差异。然而，产生腹侧面部特异性 N200 的皮质斑块在右半球更大。纹外皮层同一区域的其他皮层斑块产生光栅敏感的 N180 和物体特异性或字母串特异性的 N200，这表明人类腹侧物体识别系统被分成功能上离散的区域。
This and the following two papers describe event-related potentials (ERPs) evoked by visual stimuli in 98 patients in whom electrodes were placed directly upon the cortical surface to monitor medically intractable seizures. Patients viewed pictures of faces, scrambled faces, letter-strings, number-strings, and animate and inanimate objects. This paper describes ERPs generated in striate and peri striate cortex, evoked by faces, and evoked by sinusoidal gratings, objects and letter-strings. Short-latency ERPs generated in striate and peristriate cortex were sensitive to elementary stimulus features such as luminance. Three types of face-specific ERPs were found: (i) a surface negative potential with a peak latency of similar to 200 ms (N200) recorded from ventral occipitotemporal cortex, (ii) a lateral surface N200 recorded primarily from the middle temporal gyrus, and (iii) a late positive potential (P350) recorded from posterior ventral occipitotemporal, posterior lateral temporal and anterior ventral temporal cortex. Face specific N200s were preceded by P150 and followed by P290 and N700 ERPs. N200 reflects initial face-specific processing, while P290, N700 and P350 reflect later face processing at or near N200 sites and in anterior ventral temporal cortex. Face specific N200 amplitude was not significantly different in males and females, in the normal and abnormal hemisphere, or in the right and left hemisphere. However, cortical patches generating ventral face-specific N200s were larger in the right hemisphere. Other cortical patches in the same region of extrastriate cortex generated grating sensitive N180s and object-specific or letter-string specific N200s, suggesting that the human ventral object recognition system is segregated into functionally discrete regions.