Acupuncture combined with Tongxieyaofang for diarrhea-type irritable bowel syndrome: A protocol for meta-analysis.
Acupuncture combined with Tongxieyaofang for diarrhea-type irritable bowel syndrome: A protocol for meta-analysis.
复制标题
针灸与Tongxieyaofang结合使用腹泻型肠易激综合征：荟萃分析方案。
DOI：
10.1097/md.0000000000023457
复制
发表时间：
2020-11-25
期刊：
影响因子：
1.6
通讯作者：
Feng PM
中科院分区：
文献类型：
--
作者：
Li YL;Yao CJ;Lei R;Xie F;Xiong Q;Luo LH;Feng PM
针灸作为一种传统的中医外治方法，具有操作简单、治疗效果显着、副作用少的特点。痛泻要方（TXYF）是一种中成药，结合针灸已广泛用于治疗腹泻型肠易激综合征（IBS-D）。然而，TXYF联合针灸治疗IBS-D的疗效和安全性尚不清楚。本研究旨在验证TXYF联合针灸治疗IBS-D的有效性和安全性。自建库至2020年10月20日，TXYF联合针刺治疗所有IBS-D的随机对照试验将在PubMed、Cochrane图书馆、Embase、Web of Science、中国知识基础设施、万方数据库、中国科技期刊数据库、中国生物医学文献数据库中检索。并在百度学术、谷歌学术、国际临床试验注册平台、中国临床试验注册中心检索以获得更多相关研究全面地。方法学质量，包括偏倚风险，将使用 Cochrane 偏倚风险评估工具进行评估，而累积证据的置信度将使用建议评估、制定和评估分级 (GRADE) 方法进行评估。两名研究人员将独立进行数据提取和偏倚风险评估。统计分析将在RevMan 5.3中进行。根据目前的证据，将评估 TXYF 联合针灸治疗 IBS-D 的疗效和安全性的潜在等级。该研究结果将为TXYF联合针灸治疗IBS-D的有效性和安全性提供有益的证据，促进临床实践和进一步的科学研究。
As a traditional Chinese medicine external treatment method, acupuncture is characterized by simple operation, significant treatment effect and few side effects. Tong-Xie-Yao-Fang (TXYF), a Chinese patent medicine, combined with acupuncture has been widely used on treating Diarrhea Predominant Irritable Bowel Syndrome (IBS-D). However, the efficacy and safety of TXYF combined with acupuncture for the treatment of IBS-D are unclear. This study aims to investigate verify the efficacy and safety of TXYF combined with acupuncture for IBS-D. Randomized controlled trials of TXYF combined with acupuncture for all IBS-D will be searched in PubMed, the Cochrane Library, Embase, Web of Science, the China National Knowledge Infrastructure, Wanfang Database, Chinese Science and Technology Periodical Database, and Chinese Biomedical Literature Database from inception to October 20, 2020. And Baidu Scholar, Google Scholar, International Clinical Trials Registry Platform, and Chinese Clinical Trials Registry will be searched to obtain more relevant studies comprehensively. The methodological qualities, including the risk of bias, will be evaluated using the Cochrane risk of bias assessment tool, while confidence in the cumulative evidence will be evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Two researchers will perform data extraction and risk of bias assessment independently. Statistical analysis will be conducted in RevMan 5.3. Based on the current evidence, the potential rank of the efficacy and safety of TXYF plus acupuncture for IBS-D will be assessed. The findings of the study will provide helpful evidence for the efficacy and safety of TXYF combined with acupuncture in the treatment of IBS-D, facilitating clinical practice and further scientific studies.