Bioinformatics on a national scale: an example from Switzerland
Bioinformatics on a national scale: an example from Switzerland
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DOI：
10.1093/bib/bbx073
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发表时间：
2019-03-01
影响因子：
9.5
通讯作者：
Durinx, Christine
中科院分区：
文献类型：
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作者：
Gerritsen, Vivienne Baillie;Palagi, Patricia M.;Durinx, Christine
自20世纪80年代初以来，瑞士一直是生物信息学领域的先驱。随着时间的推移，人们认识到需要一个实体在全国范围内收集和代表生物信息学，并于1998年成立了SIB瑞士生物信息学研究所。因此，2018年是研究所成立20周年。今天，该研究所联合了全国65个研究和服务小组，这些小组的活动领域从基因组学、蛋白质组学、医学和健康到结构生物学、系统生物学、系统发展和进化，以及一个唯一任务致力于培训的小组。该研究所拥有12个能力中心，为全国各地的生命科学家提供生物信息学和生物定位专业知识。SIB很早就意识到，现代医学技术产生的丰富数据和患者日益增长的自我意识即将彻底改变考虑医疗数据的方式。2012年，它创建了一个临床生物信息学小组，以解决个性化健康问题，从而努力制定更全球化的患者管理方法，以及更有针对性和更有效的治疗方法。在这方面，SIB在瑞士个性化健康网络中发挥着重要作用，为全国各地的研究提供与患者相关的数据。该研究所治理结构的独特性也启发了其他欧洲生命科学组织的结构，特别是长生不老药。
Switzerland has been a pioneer in the field of bioinformatics since the early 1980s. As time passed, the need for one entity to gather and represent bioinformatics on a national scale was felt and, in 1998, the SIB Swiss Institute of Bioinformatics was created. Hence, 2018 marks the Institute's 20th anniversary. Today, the Institute federates 65 research and service groups across the countrywhose activity domains range from genomics, proteomics, medicine and health to structural biology, systems biology, phylogeny and evolutionand a group whose sole task is dedicated to training. The Institute hosts 12 competence centres that provide bioinformatics and biocuration expertise to life scientists across the country. SIB sensed early on that the wealth of data produced by modern technologies in medicine and the growing self-awareness of patients was about to revolutionize the way medical data are considered. In 2012, it created a Clinical Bioinformatics group to address the issue of personalized health, thus working towards a more global approach to patient management, and more targeted and effective therapies. In this respect, SIB has a major role in the Swiss Personalized Health Network to make patient-related data available to research throughout the country. The uniqueness of the Institute's governance structure has also inspired the structure of other European life science organizations, notably ELIXIR.